Table 5.
Summary of predicted associations by ADE
| ADE | Real associations | Predicted associations | Average time saving | Average probability | Top associated drug |
|---|---|---|---|---|---|
| Acute renal failure | 32 | 26 (81%) | 3.62 | 0.7655 | Ceftazidime (2)* |
| Agranulocytosis | 12 | 10 (83%) | 5.70 | 0.8293 | Albendazole (6) |
| Anemia | 9 | 6 (67%) | 2.67 | 0.7277 | Ribavirin (3) |
| Leukopenia | 4 | 4 (100%) | 3 | 0.9436 | Dexamethasone (1) |
| Myocardial infarction | 27 | 18 (67%) | 3.72 | 0.7035 | Doxazosin (5) |
| Neutropenia | 17 | 12 (71%) | 3.83 | 0.7739 | Flucytosine (2) |
| Rhabdomyolysis | 40 | 27 (68%) | 3.92 | 0.6910 | Doxylamine (0) |
| Thrombocytopenia | 10 | 7 (70%) | 3.50 | 0.7517 | Tamoxifen (0) |
*
Numbers in front of drug names in the last column indicate the number of years the model predicted their associations with the corresponding ADE earlier than it was published in PubMed.