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. 2020 Sep 28;22(6):4857–4867. doi: 10.3892/mmr.2020.11542

Table II.

Univariate and multivariate Cox regression survival analyses of the prognostic factors of glioma.

Overall survival

Univariate analysis Multivariate analysis


Clinical parameter HR 95% CI P-value HR 95% CI P-value
TPTEP1 expression (low vs. high) 2.572 (1.516–4.366) <0.001 2.143 (1.062–3.554) 0.031
Age, years (≤median vs. >median) 0.481 (0.287–0.808) 0.007 0.590 (0.331–1.054) 0.075
Sex (female vs. male) 0.660 (0.389–1.119) 0.118 0.736 (0.407–1.330) 0.310
WHO grade (I–II vs. III–IV) 0.073 (0.041–0.128) <0.001 0.427 (0.238–0.821) 0.010
Recurrence (no vs. yes) 0.095 (0.056–0.161) <0.001 0.485 (0.269–0.974) 0.043

TPTEP1, transmembrane phosphatase with tensin homology pseudogene 1; WHO, World Health Organization; HR, hazard ratio; CI, confidence interval.