Table 1.
Clinical subtypes of MSA, PSP, CBD and FTLD
| Disorder | Clinical phenotypes | Comment |
|---|---|---|
| MSA | MSA-P | Parkinsonian variant |
| MSA-C | Cerebellar variant | |
| PSP | PSP-RS | Richardson’s syndrome (classical phenotype) |
| PSP-P | Parkinsonian variant | |
| PSP-OM | Predominance of ocular motor symptoms | |
| PSP-PI | Predominance of postural instability | |
| PSP-PPFGa | Primary progressive freezing of gait | |
| PSP-PA | Pure akinesia | |
| PSP-F | PSP with frontal lobe dysfunction, including: | |
| bvFTD | PSP presenting as bvFTD | |
| PSP-CBS | PSP presenting as CBS | |
| PSP-SL | PSP with speech or language impairment, including: | |
| PSP-navPPA | PSP presenting as non-fluent agrammatic variant PPA | |
| PSP-AOS | PSP presenting as primary progressive apraxia of speech | |
| PSP-C | Cerebellar variant | |
| PSP-PLS | Primary lateral sclerosis variant | |
| CBD | CBS | Classical phenotype (possible versus probable CBS) |
| FBS | Frontal behavioral-spatial syndrome | |
| PSPS | PSP syndrome with CBD pathology | |
| navPPA | Non-fluent agrammatic variant PPA with CBD pathology | |
| FTLD | bvFTD | Behavioral variant FTD |
| svPPA | Semantic variant PPA | |
| navPPA | Non-fluent agrammatic variant PPA | |
| lvPPA | Logopenic variant PPA | |
| FTD-MND | FTD associated with motor neuron disease | |
| CBS | CBS with FTLD pathology | |
| PSP | PSP with FTLD pathology |
a
PSP-PPFG is also called PSP-PAGF: pure akinesia with gait freezing.