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. 2020 Oct 21;22(6):5113–5124. doi: 10.3892/mmr.2020.11624

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Copyright: © Chen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 6. — Therapeutic effects of narasin in the mouse left ventricle injection breast tumor metastasis model. (A) Representative bioluminescent imaging of mice injected with MCF-7-Luc cells in control and treatment groups. (B) Quantization of whole-body bioluminescence (total photon flux). **P<0.01, ***P<0.001 vs. the control group. (C) Narasin had no significant effect on the body weight of mice. (D) Western blotting was performed to determine the protein expression of p-SMAD2/3 and p-STAT3. A total of 3 tumors were randomly selected from different groups, and the experiments were repeated three times with consistent results. **P<0.01, ****P<0.0001. p-, phosphorylated.