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Sal B treatment significantly reduces the mRNA expression levels of NLRP3, ASC, caspase-1 and IL-1β in rat hearts as detected by reverse transcription-quantitative PCR analysis (n=3 rats/group). The mRNA expression levels were normalized to those of GAPDH. #P<0.05, ##P<0.01 vs. the control group; *P<0.05, **P<0.01 vs. the model group. ASC, apoptosis-associated speck like protein; NLRP3, NLR family pyrin domain-containing 3; Sal B, salvianolic acid B.
