Figure 3.

Effects of CRT on H&E staining in ATO-induced cardiotoxicity in rats. (A) Myocardial tissue obtained from the Con, ATO, CRT-L and CRT-H groups. Histopathological changes are indicated by white arrows. (B) Pathological damage scores of the heart tissue in the Con, ATO, CRT-L and CRT-H groups. Scale bar, 50 µm. Data are presented as the mean ± SEM for each group, n=10. **P<0.01 vs. Con group; ^##P<0.01 vs. ATO group. CRT, crocetin; Con, control; ATO, arsenic trioxide; CRT-L, ATO + low concentration of CRT treatment group; CRT-H, ATO + high concentration of CRT treatment group; H&E, hematoxylin and eosin.