Figure 5.

Actions of CRT on ROS in rat heart tissue using the fluorescent probe dihydroethidium. Effect of CRT and ATO on ROS generation in the heart tissue of Con, ATO, CRT-L and CRT-H animals. Areas with ROS generation are indicated by white arrows. Data are presented as the mean ± SEM for each group, n=10. **P<0.01 vs. Con group; ^##P<0.01 vs. ATO group. CRT, crocetin; Con, control; ATO, arsenic trioxide; CRT-L, ATO + low concentration of CRT treatment group; CRT-H, ATO + high concentration of CRT treatment group; ROS, reactive oxygen species; IOD.