Figure 9.

Effects of CRT on the expression levels of Bax and Bcl-2 in ATO-induced cardiotoxicity in rats as detected via immunohistochemistry. Morphological location of (A) Bax expression and (B) Bcl-2 expression. Immunoreactive Bax and Bcl-2 areas are indicated by white arrows. Quantification of the % area of (C) Bax expression and (D) Bcl-2 expression. Scale bar, 50 µm; magnification, ×400. Data are presented as the mean ± SEM for each group, n=10. **P<0.01 vs. Con group; ^##P<0.01 vs. ATO group. CRT, crocetin; Con, control; ATO, arsenic trioxide; CRT-L, ATO + low concentration of CRT treatment group; CRT-H, ATO + high concentration of CRT treatment group.