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. 2020 Oct 19;22(6):5378–5384. doi: 10.3892/mmr.2020.11612

Figure 1.

Figure 1.

Dex attenuates histopathological injury in rat lungs. (A) Hematoxylin and eosin staining of rat lung tissue (magnification, ×200; scale bar, 50 µm). The arrow indicates congestion and edema (B) The histopathological scores of degree of lung injury. Data are expressed as the mean ± SD (n=6). *P<0.05, **P<0.01 vs. Sham; #P<0.05, ##P<0.01 vs. VILI; &P<0.05 VILI+L-Dex+PD vs. VILI+L-Dex; $$P<0.01 VILI+H-Dex+PD vs. VILI+H-Dex. Dex, dexmedetomidine; H-Dex, high dose Dex at 10 µg/kg; L-Dex, low dose Dex at 1 µg/kg; PD, PD98059; VILI, ventilator-induced lung injury.