Table 2. Factors associated with extended spectrum beta-lactamase-producing Enterobacterales colonisation determined by univariate analyses and binomial logistic regression.
| Colonised N = 96 n (%) | Not colonised N = 104 n (%) | OR (95% CI) | aOR (95% CI) | |
|---|---|---|---|---|
| Male gender | 38 (39.6) | 41 (39.4) | 1.01 (0.57–1.78) | |
| Age < 12 months | 55 (57.3) | 43 (41.3) | 1.90 (1.09–3.34) * | 1.36 (0.70–2.65) |
| Transferred to RCWMCH@ | 10 (10.4) | 9 (8.7) | 1.23 (0.48–3.16) | |
| Previous RCWMCH admission | 23 (24.0) | 15 (14.4) | 1.87 (0.91–3.84) | 1.23 (0.52–2.91) |
| Current admission to medical ward (vs. surgical ward) | 63 (65.6) | 49 (47.1) | 2.14 (1.21–3.79) * | 0.78 (0.35–1.77) |
| Hospitalisation for >7 days before enrolment | 40 (41.7) | 20 (19.2) | 3.0 (1.59–5.66) * | 2.83 (1.40–5.72) * |
| Cardiac co-morbidity | 8 (8.3) | 4 (3.8) | 2.27 (0.66–7.81) | |
| Gastrointestinal tract co-morbidity | 20 (20.9) | 22 (21.2) | 0.98 (0.50–1.94) | |
| Neurological co-morbidity | 17 (17.7) | 16 (15.4) | 1.18 (0.56–2.50) | |
| Concomitant chronic lung disease | 7 (7.3) | 3 (2.9) | 2.65 (0.67–10.55) | 2.67 (0.57–12.59) |
| Concomitant congenital anomaly | 25 (26.0) | 25 (24.0) | 1.11 (0.59–2.11) | |
| Major surgery in current admission | 12 (12.5) | 23 (22.1) | 0.50 (0.24–1.08) | 0.40 (0.15–1.04) |
| Peripheral venous line | 88 (91.7.7) | 87 (83.7) | 2.15 (0.88–5.24) | 1.81 (0.65–5.02) |
| Nasotracheal intubation ± ventilation | 8 (8.3) | 4 (3.8) | 2.27 (0.66–7.81) | |
| PEG feeding | 6 (6.2) | 1 (1.0) | 6.87 (0.81–58.1) | |
| Nasogastric intubation | 38 (39.6) | 24 (23.1) | 2.18 (1.18–4.03) * | 1.60 (0.76–3.39) |
| Decreased level of consciousness | 5 (5.2) | 1 (1.0) | 5.66 (0.65–49.3) | |
| Receiving gastric acid inhibitor therapy | 12 (12.5) | 6 (5.8) | 2.33 (0.84–6.49) | |
| Receiving immunosuppressive therapy | 11 (11.2) | 11 (10.6) | 1.09 (0.45–2.65) | |
| Admission to ICU in 12 months preceding current admission | 6 (6.2) | 2 (1.9) | 3.40 (0.68–17.27) | |
| Admission to ICU during current admission | 19 (19.8) | 15 (14.4) | 1.46 (0.70–3.08) | |
| Antibiotic administration in the 12-month period preceding admission | 29 (30.2) | 21 (20.2) | 1.71 (0.90–3.27) | 1.35 (0.63–2.90) |
*p<0.05, OR Odds ratio, 95% CI 95% confidence interval, aOR adjusted Odds ratio, RCWMCH Red Cross War Memorial Children’s Hospital, PEG percutaneous endoscopic gastrostomy, ICU intensive care unit. @Tranfered to RCWMCH refers to admitted from another hospital or a convalescent home.