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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Trends Cell Biol. 2020 Aug 13;30(10):764–776. doi: 10.1016/j.tcb.2020.07.003

Table 1:

Relevant mouse models.

Model Primary organ site Lineage label Definition of EMT Reference
MMTV-PyMT
MMTV-Cre
Breast RosaLSL-YFP
Ecad-mCFP
YFP+/mCFPlow EMT cells [17]
MMTV-PyMT Breast Fsp-Cre
RosaloxP-RFP-STOP-loxP-GFP
RFP−/GFP+ EMT cells after Fsp-cre mediated recombination [18]
MMTV-Her2/c-neu/Erbb2 Breast Snail-YFP YFP+ EMT cells after induction of Snail during EMT [21]
“KPCY”
KrasLSL-G12D
p53LSL-R172H or loxP
Pdx1-Cre
Pancreas RosaLSL-YFP YFP+/ECAD− EMT cells [22]
Pb-Cre
PtenloxP/loxP
KrasLSL-G12D
Prostate Vimentin-GFP GFP+/EpCAM− EMT cells after induction of Vimentin during EMT [24]
AT3 tumor cell injection Prostate CMV-loxP-DsRed-Stop-loxP-eGFP RFP+ cells that have undergone EMT and GFP+ cells that remain epithelial [71]