Table 1.

Drug-route complexity criteria classification

ISMP	RPh Survey	Unique Order Sentences	Drug-Route Dyads
High Complexity
Y	>35	>15	Heparin IV
Y	>35	6<X<15	Lidocaine IV
Y	>35	<5	Fentanyl IV a , Metoprolol IV, Labetalol IV,
			Norepinephrine IV a , Amiodarone IV a ,
			Morphine IV a
Y	26<X<35	>15	None
Y	<26	>15	None
Moderate Complexity
Y	26<X<35	6<X<15	None
Y	26<X<35	<5	Oxycodone PO, Magnesium sulfate IV,
			Dexamethasone IV a
Y	<26	6<X<15	None
N	26<X<35	6<X<15	Prednisone PO
N	>35	6<X<15	Quetiapine PO, Tacrolimus PO
N	26<X<35	>15	None
Low Complexity
N	<26	<5	Senna PO a , Aspirin PO a , Amlodipine PO, Atorvastatin POa, Multivitamins PO, Acetaminophen PO
N	<26	6<X<15	None
N	<26	>15	None
N	26<X<35	<5	Potassium chloride PO, Lisinopril PO, Albumin IV, Gabapentin PO, Ondansetron PO, Furosemide IV
N	>35	<5	Piperacillin-tazobactam IV b , Cefazolin IVa,
			Pantoprazole IV, Lorazepam IV

^a BOLD = selected for study.

^b BOLD = selected for study and reclassified to moderate complexity.