Table 2.
Informative, identifying features of clusters for data transformations A and B, in order of overall survival
| Data Transformation A. | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| ID | n | Sexa | IGHV Status | ZAP70 | Döhner | CD38 | Light Chain | Other | |
| A1 | 19 | M | Mutated | − | Low | Lambda | Hypogammaglobulinemia | ||
| A2 | 29 | F | Mutated | − | del13q | Low | |||
| A3 | 36 | M | Mutated | − | del13q | Low | |||
| A4 | 27 | M | Unmutated | High | Kappa | ||||
| A5 | 25 | M | Unmutated | − | Low | Anemia | |||
| A6 | 38 | Unmutated | + | Low | Kappa | ||||
| A7 | 22 | Unmutated | + | Low | Anemia | ||||
|
| |||||||||
| Data Transformation B. | |||||||||
| ID | n | Sex a | IGHV Status | ZAP70 | CD38 | Age (yrs) | Prolymphocytes (%) | Light Chain | Otder |
| B1 | 46 | Mutated | − | Low | < 65 | < 10 | Lambda | ||
| B2 | 37 | Mutated | − | Low | < 65 | < 10 | Kappa | ||
| B3 | 26 | M | Unmutated | < 65 | < 10 | Anemia | |||
| B4 | 44 | Unmutated | + | Low | < 65 | < 10 | Kappa | ||
| B5 | 12 | M | Unmutated | + | Low | ≥ 65 | Lambda | Anemia | |
| B6 | 31 | M | Unmutated | + | High | < 65 | < 10 | Kappa | |
Notes: Clusters are ordered by predicted survival outcome, from longest survival (A1 or B1) to shortest (A7 or B6). Characteristic features of each cluster, defined as a feature present in at least 75% of members of a given cluster, include known indicators of superior prognosis (IGHV-mutated status and female sex) and poor prognosis (ZAP70 positivity). For complete results and percentages, see Supplementary Table B.1.
a
M, male; F, female.