Table 1.
Characteristics | Frequency (%) |
---|---|
Demographics | |
Mean age ± SD (range) | 61.6 ± 10.1 (38–83) |
Sex | |
Female | 19 (40.4%) |
Male | 28 (59.6%) |
Race | |
Nonwhite | 4 (8.5%) |
White | 43 (91.5%) |
Primary tumor | |
Mean tumor size, cm | 7.5 ± 4.0 |
Histology | |
Non-clear cell renal cell carcinoma | 6 (12.8%) |
Clear cell renal cell carcinoma | 41 (87.2%) |
Grade | |
1 | 1 (2.1%) |
2 | 8 (17.0%) |
3 | 23 (48.9%) |
4 | 11 (23.4%) |
N/A | 4 (8.5%) |
pT | |
pT1 | 15 (31.9%) |
pT2 | 5 (10.6%) |
pT3 | 23 (48.9%) |
N/A | 4 (8.5%) |
pN | |
pN0 | 10 (21.3%) |
pN1 | 3 (6.4%) |
pNX | 29 (61.7%) |
N/A | 5 (10.6%) |
M* | |
M0 | 34 (72.3%) |
M1 | 11 (23.4%) |
N/A | 2 (4.3%) |
Risk score† | |
0, Favorable | 20 (42.6%) |
1–2, Intermediate/unfavorable | 16 (34.0%) |
N/A | 11 (23.4%) |
Metastasis | |
Sum of largest diameters, cm (range) | 4.5 ± 3.5 (0.8–14.8) |
No. of metastases treated, initial‡ | |
1 | 35 (74.5%) |
2 | 7 (14.9%) |
3 | 4 (8.5%) |
4 | 1 (2.1%) |
No. of metastases treated, total§ | |
1 | 26 (55.3%) |
2 | 12 (25.5%) |
3 | 4 (8.5%) |
≥4 | 5 (10.6%) |
Treatment sites‡ | |
Bone | 28 (43.1%) |
Lung | 10 (15.4%) |
Liver | 6 (9.2%) |
Soft tissue | 6 (9.2%) |
Lymph node | 5 (7.7%) |
Adrenal | 4 (6.2%) |
Others | 6 (9.2%) |
Radiation therapy‡ | |
22.1 ± 4.0 Gy × 1 fraction | 14 (21.5%) |
12.8 ± 2.2 Gy × 3 fractions | 21 (32.3%) |
8.0 ± 1.4 Gy × 5 fractions | 30 (46.2%) |
M stage at presentation.
Heng’s criteria measured at the start of stereotactic ablative radiotherapy (SAbR).
During initial SAbR course.
During all SAbR courses before systemic therapy.