Table 1.
Basal information of septic patients with AKI at day 1 of ICU admission
| Characteristics | Survivors | Nonsurvivors | p |
|---|---|---|---|
| Patients | 26 | 41 | |
| Age (years) | 61.0 ± 2.9 | 59.0 ± 2.9 | 0.934 |
| Gender (male/female) | 12/14 | 24/17 | 0.899 |
| Temperature (°C) | 37.4 ± 0.21 | 37.2 ± 0.18 | 0.621 |
| Respiration (bpm) | 26 ± 2 | 29 ± 1 | 0.063 |
| SBP (mmHg) | 97 ± 5 | 101 ± 5 | 0.403 |
| DBP (mmHg) | 59 ± 3 | 59 ± 3 | 0.223 |
| APACHE II score | 16.9 ± 3.1 | 17.2 ± 2.8 | 0.698 |
| Mechanical | 15/11 | 4/37 | 0.437 |
| Ventilation (no/yes) | |||
| CRRT (no/yes) | 2/24 | 7/34 | 0.01 |
| Urine output(average) (mL/h) | 26 | 17 | 0.027 |
| Causes of sepsis (%) | |||
| Pneumonia | 69 | 72 | |
| BSI | 14 | 17 | |
| Urosepsis | 8 | 4 | |
| GI/biliary | 5 | 6 | |
| Others | 4 | 1 | |
| WBC (109/L) | 17.8 ± 2.7 | 12.8 ± 2.3 | 0.199 |
| LY (109/L) | 0.86 ± 0.15 | 0.97 ± 0.17 | 0.605 |
| PLT (109/L) | 71 ± 9 | 113 ± 12 | 0.009 |
| PLR | 115 ± 14 | 208 ± 20 | 0.000 |
| BUN (mmol/L) | 14.9 (11.2, 17.2) | 16.1 (11.4, 21.4) | 0.000 |
| SCr (μmol/L) | 244 (178.4, 269.6) | 242.8 (164.3, 300.5) | 0.087 |
| Lac (mmol/L) | 4.3 (2.8, 5.1) | 6.2 (2.5, 8.9) | 0.005 |
| PCT (mmol/L) | 65.3 (18.2, 100) | 59.2 (10.9, 100) | 0.000 |
AKI = acute kidney injury; APACHE = acute physiology and chronic health evaluation; BSI = blood strem infection; BUN = blood urea nitrogen; CRRT = continuous renal replacement treatment; DBP = diastole blood pressure; GI = gastrointestinal infection; Lac = lactate; LY = lymphocyte; PCT = procalcitonin; PLR = platelet/lymphocyte ratio; PLT = platelet; SBP = systolic blood pressure; SCr = serum creatinine; WBC = white blood cell.