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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: J Thromb Haemost. 2020 Apr 9;18(6):1370–1380. doi: 10.1111/jth.14790

Table 3.

Kinetic effects of gCΔ457t compared to sTF on FX activation.

Cofactor Lipid Km (μM) kcat (s−1) kcat/Km (μM−1 s−1)
sTF-His NiPCPS 0.16 ± 0.02 3.8 ± 0.5 23.6 ± 1.4
gCΔ457t NiPCPS 0.14 ± 0.02 2.5 ± 0.3 16.6 ± 1.0