Table 1.
Demographic and clinical characteristics of DES-ISR patients after PCI.
| Variables | Early ISR (n = 32) | Late ISR (n = 218) | P |
| Age (years) | 58.5 (48.8–63.8) | 61 (54.0–67.0) | 0.103 |
| Male | 22 (22.0) | 176 (80.7) | 0.119 |
| BMI (kg/m2) | 26.2 (24.0–28.1) | 25.8 (24.1–27.7) | 0.844 |
| Diabetes mellitus | 12 (37.5) | 83 (38.1) | 0.950 |
| Hypertension | 21 (65.6) | 150 (68.8) | 0.718 |
| Dyslipidemia | 26 (81.3) | 196 (89.9) | 0.144 |
| Apoplexy | 5 (15.6) | 29 (13.3) | 0.782 |
| Atrial fibrillation | 2 (6.3) | 9 (4.1) | 0.637 |
| CKD | 1 (3.1) | 4 (1.8) | 0.499 |
| Prior MI | 12 (37.5) | 65 (29.8) | 0.379 |
| Prior CABG | 1 (3.1) | 7 (3.2) | 1.000 |
| Prior surgery | 4 (12.5) | 42 (19.3) | 0.356 |
| Peripheral vascular history | 1 (3.1) | 15 (6.9) | 0.702 |
| History of smoking | 17 (53.1) | 134 (61.5) | 0.368 |
| Smoking within 1 month | 7 (21.9) | 51 (23.4) | 0.849 |
| History of drinking | 11 (34.4) | 113 (51.8) | 0.065 |
| Family history of CHD | 7 (21.9) | 44 (20.2) | 0.825 |
| History of interruption APT | 0 (0) | 24 (11.0) | 0.052 |
| Symptoms on admission | 0.088 | ||
| Stable angina | 12 (37.5) | 39 (17.9) | – |
| Unstable angina | 19 (59.4) | 165 (75.7) | – |
| NSTEMI | 1 (3.1) | 8 (3.7) | – |
| STEMI | 0 (0) | 6 (2.8) | – |
| Killip class >II or NYHA class >II | 10 (31.3) | 100 (45.9) | 0.120 |
| Prior PCI counts | 1 (1–2) | 1 (1–2) | 0.929 |
| Stent amounts | 3 (2–4) | 2 (1–4) | 0.110 |
| Stented vessel counts | 1 (1–2) | 2 (1–2) | 0.639 |
| In-hospital time (days) | 5 (3–6) | 4 (3–5) | 0.221 |
| Period of ISR (years) | 0.8 (0.5–0.9) | 5.1 (2.4–7.5) | <0.001 |
Data are presented as median (range) or n (%). APT: Antiplatelet therapy; BMI: Body mass index; CABG: Coronary artery bypass grafting; CKD: Chronic kidney disease; DES: Drug-eluting stent; ISR: In-stent restenosis; MI: Myocardial infarction; NSTEMI: Non-ST-segment elevated myocardial infarction; NYHA: New York Heart Association; PCI: Percutaneous coronary intervention; STEMI: ST-segment elevated myocardial infarction.