Table 3.
Characteristics of PCI and clinical outcomes in patients with DES-ISR at 12-month follow-up after treatment.
| Variables | Early ISR (n = 32) | Late ISR (n = 218) | P value |
| Prior PCI characteristics | |||
| Single vessel lesion | 5 (15.6) | 46 (21.1) | 0.473 |
| Including lesion of LM | 3 (9.4) | 8 (3.7) | 0.154 |
| Calcific lesions | 15 (46.9) | 121 (55.5) | 0.360 |
| Pre-Procedure TIMI flow grade∗ | |||
| 0 | 10 (31.3) | 32 (14.7) | 0.019 |
| 1–2 | 5 (15.6) | 34 (15.6) | 1.000 |
| 3 | 17 (53.1) | 150 (68.8) | 0.079 |
| Post-procedural TIMI flow grade 3 | 32 (100) | 218 (100) | – |
| Residual stenosis >30% | 0 | 1 (0.5) | 1.000 |
| Complication | 0 | 1 (0.5) | 1.000 |
| Treatment for ISR | 0.652 | ||
| Implanting stent | 22 (68.8) | 141 (64.7) | – |
| Balloon angioplasty | 10 (31.2) | 77 (35.3) | – |
| Presentation with MI | 1 (3.1) | 14 (6.4) | 0.701 |
| Outcome of index PCI | 0.615 | ||
| Success | 30 (93.8) | 207 (95.0) | – |
| Part success | 1 (3.1) | 8 (3.7) | – |
| Failure | 1 (3.1) | 3 (1.4) | – |
| Follow-up at 12 months | |||
| Re-hospitalization | 12 (37.5) | 16 (7.3) | <0.001 |
| MACE events | 12 (37.5) | 12 (5.5) | <0.001 |
| Cardiac death | 0 | 1 (0.5) | 1.000 |
| Non-fatal MI | 0 | 0 | – |
| Target lesion revascularization | 12 (37.5) | 11 (5.0) | <0.001 |
| Stent thrombosis | 0 | 1 (0.5) | 1.000 |
∗
There were two cases in late ISR lacking the pre-TIMI flow grade. Data are presented as n (%). DES: Drug-eluting stent; ISR: In–stent restenosis; LM: Left main coronary artery; MACE: Major adverse cardiac events; PCI: Percutaneous coronary intervention; TIMI: Thrombolysis in myocardial infarction.