Table 5.
KEGG analysis of targeted genes in competitive endogenous RNA crosstalk associated with THCA.
| Ontology source | GO term | P | Genes |
| KEGG | Alanine, aspartate, and glutamate metabolism | .00 | ABAT, ALDH4A1, ASS1 |
| KEGG | Drug metabolism | .01 | ADH1C, ADH6, FMO5 |
| KEGG | Glycine, serine, and threonine metabolism | .00 | DAO, GLDC, PSAT1 |
| KEGG | Glycolysis/Gluconeogenesis | .00 | ADH1C, ADH6, ENO2, FBP1, HK2, PCK1 |
| KEGG | HIF-1 signaling pathway | .00 | EGF, EGLN3, ENO2, HK2, TIMP1 |
| KEGG | Melanoma | .01 | EGF, FGF1, FGF9 |
| KEGG | PPAR signaling pathway | .01 | ANGPTL4, FABP7, PCK1 |
| KEGG | Tyrosine metabolism | .00 | ADH1C, ADH6, HPD |
| REACTOME | Constitutive Signaling by Aberrant PI3K in Cancer | .00 | EGF, ERBB4, FGF1, FGF9 |
| REACTOME | Glyoxylate metabolism and glycine degradation | .00 | ALDH4A1, DAO, GLDC |
| REACTOME | Histidine, lysine, phenylalanine, tyrosine, proline, and tryptophan catabolism | .00 | ALDH4A1, HPD, IDO1 |
| REACTOME | PI3K inhibitors block PI3K catalytic activity | .00 | EGF, ERBB4, FGF1, FGF9 |
| REACTOME | SLC transporter disorders | .01 | CP, SLC12A3, SLC34A1 |
| REACTOME | Transport of bile salts and organic acids, metal ions, and amine compounds | .00 | CP, SLC22A7, SLC30A2, SLC47A2, SLC5A11 |
| REACTOME | Exocytosis of platelet alpha granule contents | .00 | EGF, KNG1, PLG, TIMP1 |
| Wiki Pathways | Complement and Coagulation Cascades | .01 | C3, KNG1, PLG |
| Wiki Pathways | Lung fibrosis | .01 | EGF, FGF1, TIMP1 |
| Wiki Pathways | Pathways in clear cell renal cell carcinoma | .00 | BHLHE41, ENO2, HK2, LDHD, PSAT1 |
| Wiki Pathways | Primary Focal Segmental Glomerulosclerosis FSGS | .01 | NPHS1, NPHS2, PTPRO |
| Wiki Pathways | Zinc homeostasis | .00 | MT1F, MT1G, SLC30A2 |