Table 3.

Meta-analysis of the association between 18 polymorphisms of 7 genes and pediatric asthma risk in Chinese.

				Test of association		Test of heterogeneity			Begg test
Gene	Polymorp-hism	Comparison	N	OR (95%CI)	P	Model	Ph	I2/%	z	P
IL-13	+2044G/A	A vs G	4	1.70 (1.38–2.09)	.00	F	0.21	34.3	1.70	.09
		GA+AA vs GG		2.29 (1.69–3.11)	.00	F	0.19	36.7	0.34	.73
	−1112C/T	T vs C	4	1.12 (0.61–2.03)	.72	R	0.00	93.5	−0.24	1.00
		CT+TT vs CC		1.15 (0.58–2.30)	.69	R	0.00	92.5	−0.24	1.00
	+1923C/T	T vs C	3	1.06 (0.46–2.42)	.89	R	0.00	91.2	0.00	1.00
		CT+TT vs CC		1.13 (0.38–3.36)	.82	R	0.00	90.2	0.00	1.00
IL-4	−590C/T	T vs C	10	1.28 (1.01–1.61)	.04	R	0.00	75.1	0.18	.86
		CT+TT vs CC		1.73 (1.34–2.23)	.00	F	0.25	21.0	0.89	.37
ADRB2	−46 G /A	G vs A	7	0.96 (0.67–1.36)	.80	R	0.00	87.1	0.30	.76
		GA+GG vs AA		0.99 (0.65–1.51)	.96	R	0.00	80.1	0.00	1.00
	−79G/C	G vs C	3	1.05 (0.65–1.71)	.83	R	0.01	79.6	0.00	1.00
		GC+GG vs CC		1.12 (0.63–1.98)	.71	R	0.00	79.2	0.00	1.00
ADAM33	F+1	T vs C	3	1.02 (0.87–1.21)	.77	F	0.60	0.0	1.04	.30
		CT+TT vs CC		1.05 (0.85–1.31)	.63	F	0.89	0.0	1.04	.30
	V4	G vs C	3	0.74 (0.22–2.17)	.62	R	0.00	98.2	0.00	1.00
		GC+GG vs CC		0.72 (0.15–3.60)	.69	R	0.00	95.1	0.00	1.00
	S2	C vs G	4	0.80 (0.57–1.12)	.19	R	0.03	67.4	0.34	.74
		GC+CC vs GG		0.52 (0.17–1.60)	.26	R	0.01	76.0	0.34	.73
	T2	A vs G	3	2.26 (1.29–3.94)	.00	R	0.00	84.5	0.00	1.00
		AG+AA vs GG		2.29 (1.25–4.17)	.01	R	0.00	83.4	0.00	1.00
	T1	G vs A	3	1.72 (0.95–3.14)	.07	R	0.00	90.5	0.00	1.00
		GA+GG vs AA		2.92 (2.35–3.63)	.00	F	0.34	8.3	0.00	1.00
VDR	ApaI	C vs A	4	1.23 (0.40–3.77)	.72	R	0.00	90.5	1.02	.31
		CC+CA vs AA		1.28 (0.31–5.18)	.73	R	0.00	90.7	0.73	.46
	FokI	C vs T	3	0.88 (0.53–1.48)	.64	R	0.05	67.3	0.00	1.00
		CC+CT vs TT		0.79 (0.34–1.87)	.59	R	0.05	67.5	0.00	1.00
	BsmI	G vs A	5	2.09 (1.23–3.56)	.01	F	0.20	33.9	0.24	.81
		GG+GA vs AA		1.51 (0.99–2.31)	.06	R	0.11	46.8	0.73	.46