Table 1.
Characteristics of studies included in the meta-analysis.
| Q-adjusted LASIK | Standard LASIK | |||||||||||
| Authors | Year | Country | Follow-up (mo) | Laser Instrument | Eyes/Patients(n) | Age (yrs) | Preoperative SE (D) | Eyes/Patients (n) | Age (yrs) | Preoperative SE (D) | Design | NOS |
| Li et al[15] | 2012 | China | 3 | Allegretto Wave Eye-Q 400 Hz (Wavelight AG, Germany) | 32/32 | 21 ± 2.50 | DS: -4.38 ± -0.58 DC: -0.82 ± -0.25 | 16/16 | 23 ± 3.1 | DS: -3.39 ± -0.82 DC: -0.61 ± -0.46 | Cohort | 6 |
| Zheng et al[16] | 2011 | China | >6 | Technolas 217-z100 excimer laser (Bausch and Lomb) | 132/66 | 18–43 | −2.25 | 100/50 | 18–39 | −2 | Cohort | 7 |
| Zhou et al[17] | 2010 | China | 1 | Allegretto Wave Eye-Q 400 Hz (Wavelight AG) | 27/27 | 22.6 (18–35) | −4.56 ± 1.69 | 27/27 | 22.6 (18–35) | −4.38 ± 1.80 | RCT | 7 |
| Xin et al[18] | 2010 | China | 36 | Technolas 217-z100 excimer laser (Bausch and Lomb) | 367/189 | NA | NA | 194/100 | NA | NA | RCT | 6 |
| Igarashi et al[19] | 2009 | Japan | 3 | Technolas 217-z100 excimer laser (Bausch and Lomb) | 28/15 | 36.4 ± 5.8 | −5.13 ± 1.23 | 33/18 | 32.9 ± 8.3 | −5.63 ± 0.88 | Cohort | 6 |
| Villa et al[20] | 2009 | Spain | 3 | Allegretto Wave Eye-Q 400 Hz (Wavelight AG, Germany) | 48/24 a 40/40b | 32.3a 31.3b | −3.4a –4b | 76/38a 40/40b | 35.2a 31.3b | −3.7a −4b | Cohort | 8 |
| Liu et al[21] | 2008 | China | >12 | Astrascan XL 200 Hz (LaserSigh) | 106/53 | 27.9 ± 4.86 | −6.57 ± 1.81 | 102/51 | 25.4 ± 5.85 | −5.99 ± 2.53 | RCT | 7 |
| Wei et al[22] | 2008 | China | 1 | NA | 276/139 | 20.49 ± 3.31 | −4.52 ± 1.77 | 479/241 | 22.79 ± 4.42 | −4.55 ± 1.91 | Cohort | 7 |
| Ma et al[23] | 2008 | China | >6 | Allegretto Wave Eye-Q 400 Hz (Wavelight AG, Germany) | 86/43 | NA | NA | 86/43 | NA | NA | Cohort | 8 |
| Zou et al[24] | 2008 | China | 3 | Technolas 217-z100 excimer laser (Bausch and Lomb) | 152/80 | 26.56 ± 4.97 | DS: −5.79 ± −2.18 DC: −0.79 ± −0.41 | 181/100 | 25.4 ± 5.17 | DS: −5.21 ± −1.41 DC: −0.60 ± −0.49 | RCT | 8 |
| Xu et al[25] | 2008 | China | 3 | Allegretto Wave Eye-Q 400 Hz (Wavelight AG, Germany) | 46/23 | 25.5 ± 6.02 | −5.48 ± 2.38 | 44/22 | 24.7 ± 5.86 | −5.62 ± 2.63 | Cohort | 7 |
| Zhou et al[26] | 2008 | China | 6 | Mel 80 (Carl Zeis, Germany) | 38/38 | 27.1 ± 4.8 | −3.46 ± 1.62 | 41/41 | 26.4 ± 6.1 | −3.59 ± 1.68 | Cohort | 6 |
| Cai et al[27] | 2008 | China | 1 | Astrascan XL 200 Hz (LaserSigh) | 64/32 | 24.3 ± 7.2 | DS: −3.24 ± 1.21 DC: −0.46 ± 0.29 | 64/32 | 25.1 ± 6.7 | DS: −3.13 ± 1.09 DC: −0.58 ± 0.31 | RCT | 6 |
| Huang et al[28] | 2008 | China | 3 | Technolas 217-z100 excimer laser (Bausch and Lomb) | 43/43 | 23 ± 4 | -4.83 ± 1.28 | 41/41 | 25 ± 4 | −5.01 ± 1.65 | RCT | 7 |
| Chen et al[29] | 2007 | China | 6 | Astrascan XL 200 Hz (LaserSigh) | 66/33 | 24.61 ± 5.92 | −5.18 ± 1.62 | 59/30 | 24.2 ± 6.46 | −5.26 ± 1.65 | Cohort | 8 |
| Liu et al[30] | 2007 | China | 1 | Technolas 217-z100 excimer laser (Bausch and Lomb) | 51/28 | 24.65 ± 0.91 | DS: −6.71 ± 0.91 DC: −0.68 ± 0.09 | 51/26 | 23.87 ± 1.05 | DS: −6.62 ± 0.21 DC: −0.64 ± 0.07 | Cohort | 8 |
| Shen et al[31] | 2005 | China | 6 | Allegretto Wave Eye-Q 400 Hz (Wavelight AG, Germany) | 64/32 | NA | −6.22 ± 2.22 | 58/29 | NA | −6.19 ± 2.17 | Cohort | 6 |