Figure 3.

CART Cell Expansion, Persistence and Activity

(A) Frequency of B cells detected in the peripheral blood of patients with PDAC at baseline (Pre) and at day 28 after receiving a 1:1 mixture of CART-19 and CART-Meso cells. (B) Frequency of CART-19 cells and B cells in blood over time for indicated patients. (C and D) Shown is the copy number of CART-Meso/μg DNA and CART-19/μg DNA detected in the blood at (C) peak expansion and (D) the indicated time points. Statistical significance in (A) and (C) was determined with unpaired Mann Whitney test (two-tailed). ∗p < 0.05.