Table 7.
Effects of dietary taurine supplementation on the expression levels of hepatic lipid metabolism–related genes of broilers.
| Items4 | Dietary taurine concentration treatment3 |
SEM1 |
P Value |
||||
|---|---|---|---|---|---|---|---|
| CON | TAU1 | TAU2 | TAU3 | Linear2 | Quadratic2 | ||
| AMPKα | 1.000b | 1.681a,b | 2.097a | 1.780a,b | 0.179 | 0.085 | 0.159 |
| SIRT1 | 1.000b | 1.629a,b | 1.876a | 1.435a,b | 0.116 | 0.112 | 0.017 |
| CPT-1 | 1.000b | 1.467a,b | 1.630a | 1.257a,b | 0.098 | 0.271 | 0.032 |
| PPARα | 1.000b | 1.224a,b | 1.422a | 1.437a | 0.068 | 0.012 | 0.415 |
| APOA1 | 1.000b | 1.733a | 1.695a | 1.689a | 0.107 | 0.027 | 0.050 |
| SREBP-1 | 1.000a | 0.834a,b | 0.752b | 0.834a,b | 0.034 | 0.045 | 0.055 |
| FAS | 1.000a | 0.669b | 0.799a,b | 0.768a,b | 0.046 | 0.149 | 0.089 |
| ACC | 1.000 | 0.856 | 0.821 | 0.857 | 0.091 | 0.592 | 0.640 |
a,bMeans within the same row with no common superscript differ significantly (P < 0.05).
Abbreviations: ACC, acetyl-CoA carboxylase; AMPKα, adenosine monophosphate–activated protein kinase alpha; APOA1, apolipoprotein A1; CPT-1, carnitine palmitoyltransferase 1; FAS, fatty acid synthase; PPARα, peroxisome proliferator-activated receptor α; SIRT1, silent 1; SREBP-1, sterol regulatory element-binding protein-1.
Standard error of the means (n = 8).
Orthogonal polynomials were used to evaluate linear and quadratic responses to the levels of taurine treatment.
CON, basal diet; TAU1, TAU2 and TAU3 group, basal diet adding 2.50, 5.00, and 7.50 g/kg TAU, respectively.
Expressed in arbitrary units. The expression of each target gene for the CON group was assigned a value of 1 and normalized against beta actin.