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. 2020 Oct 29;2020:1359120. doi: 10.1155/2020/1359120

Table 1.

The basic characteristics of the included studies.

Study Place Mean age (years) Study design Number of eyes Gender (M/F) OCTA type RPC scan size (mm) Outcomes
Fard et al. [19] Iran 55.8 ± 10.6
51.5 ± 19.5
Cross-sectional study Cases: 33
Controls: 81
None Optovue 4.5 × 4.5 RPC whole enface VD, RPC inside disc VD, RPC peripapillary VD, p-RNFL thickness
Mastropasqua et al. [20] USA 68.1 ± 4.3
63.9 ± 7.0
Case-control study Cases: 22
Controls: 23
9/13
12/11
Optovue 4.5 × 4.5 RPC whole enface VD, RPC peripapillary VD, p-RNFL thickness
Abri Aghdam et al. [23] Iran 56.80 ± 6.81
27.90 ± 11.70
Prospective observational study Cases: 10
Controls: 10
4/6
1/6
Optovue 4.5 × 4.5 RPC whole enface VD, RPC inside disc VD, RPC peripapillary VD
Aghsaei Fard et al. [24] Iran 55.46 ± 11.38
55.26 ± 15.69
Cross-sectional study Cases: 37
Controls: 54
21/16
22/32
Optovue 4.5 × 4.5 RPC whole enface VD, p-RNFL thickness, macular GCC thickness
Al-Nashar and Hemeda [25] Egypt 60.2 ± 3.5
60.2 ± 3.5
Cross-sectional study Cases: 25
Controls: 25
14/11
14/11
Optovue 4.5 × 4.5 RPC whole enface VD, RPC inside disc VD
Augstburger et al. [26] France 66.9 ± 10.1
66.0 ± 9.2
Retrospective case-control study Cases: 26
Controls: 24
16/8
16/8
Optovue 3 × 3 FAZ-S, FAZ-D, FSVD, RPC whole enface VD, RPC peripapillary VD, p-RNFL thickness, macular GCC thickness
Fard et al.[27] USA 54.1 ± 11
58.4 ± 10.3
Cross-sectional study Cases: 31
Controls: 77
16/15
35/42
Optovue 4.5 × 4.5 RPC whole enface VD, p-RNFL thickness
Fard et al. [28] Iran 55.2 ± 11.8
47.0 ± 11.1
Cross-sectional study Cases: 29
Controls: 48
14/15
21/27
Optovue 4.5 × 4.5 RPC whole enface VD, p-RNFL thickness, macular GCC thickness
Hata et al. [29] Japan 66.4 ± 14.2
61.3 ± 19.1
Prospective observational study Cases: 15
Controls: 19
8/3
6/8
Optovue 3 × 3 RPC whole enface VD, p-RNFL thickness
Liu et al. [30] Taiwan 59.0 ± 10.7
51.4 ± 14.1
Prospective observational study Cases: 13
Controls: 18
6/7
7/11
Optovue 4.5 × 4.5 RPC whole enface VD, RPC peripapillary VD, p-RNFL thickness, macular GCC thickness
Liu et al. [31] Taiwan 59.90 ± 10.70
55.74 ± 14.51
Cross-sectional study Cases: 10
Controls: 27
4/6
14/13
Optovue 4.5 × 4.5 RPC whole enface VD, RPC peripapillary VD, p-RNFL thickness, macular GCC thickness
Pierro et al. [32] Italy 46.9 ± 12.5
47.5 ± 8.3
Cross-sectional study Cases: 15
Controls: 15
9/6
8/7
Topcon 4.5 × 4.5 RPC whole enface VD, p-RNFL thickness
Sharma et al. [33] Singapore 69 (61-82)
68 (52-82)
Observational case-control study Cases: 6
Controls: 19
3/2
None
Optovue 4.5 × 4.5 RPC whole enface VD, RPC inside disc VD
Song et al. [34] China 56.4 ± 8.38
55.57 ± 9.28
Cross-sectional study Cases: 41
Controls: 30
14/16
12/18
Optovue 4.5 × 4.5 RPC whole enface VD, RPC inside disc VD, RPC inside disc VD