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. 2020 Aug 8;99(11):6094–6118. doi: 10.1016/j.psj.2020.07.031

Table 2.

Gene ontology analysis of the differentially expressed genes (DEGs) identified in the testis compared with those in the epididymis and ductus deferens.

P value
No DEGs
Gene onthology P value
No DEGs
Testis vs. epididymis Testis vs. ductus deferens
Biological process
Cell cycle
 1.690E-13 96 Cell cycle 1.764E-11 112
 3.135E-13 82 Cell cycle process 1.562E-10 93
 1.726E-08 72 Chromosome organization 5.773E-07 84
 2.750E-09 62 DNA metabolic process 9.569E-07 69
 6.606E-14 43 Chromosome segregation 1.414E-10 45
 4.458E-14 47 Nuclear division 5.553E-08 45
 8.737E-10 34 Nuclear chromosome segregation 1.226E-05 33
 9.497E-03 32 DNA repair 3.965E-03 40
 3.673E-03 29 Cell cycle phase transition 1.064E-02 34
 3.344E-05 25 DNA replication 3.999E-08 34
 4.722E-05 23 Sister chromatid segregation 9.632E-03 23
 4.585E-03 16 DNA-dependent DNA replication 3.157E-03 19
 8.777E-07 13 Homologous chromosome segregation
 4.123E-02 11 Chromosome separation
 1.009E-03 8 DNA replication initiation
Meiosis
 1.608E-05 13 Chromosome organization involved in meiotic cell cycle 3.059E-02 11
 6.448E-05 11 Male meiotic nuclear division 1.276E-02 10
 4.985E-07 16 Meiosis I
 7.445E-07 16 Meiosis I cell cycle process
 1.662E-12 29 Meiotic cell cycle 8.020E-07 26
 5.564E-11 26 Meiotic cell cycle process 1.145E-05 23
 1.588E-06 15 Meiotic chromosome segregation 3.031E-02 12
 2.091E-11 25 Meiotic nuclear division 5.162E-06 22
Mitosis
 7.940E-08 57 Mitotic cell cycle 8.212E-08 69
 9.456E-03 26 Mitotic cell cycle phase transition
 1.875E-06 48 Mitotic cell cycle process 5.440E-06 57
 4.073E-05 27 Mitotic nuclear division 1.531E-02 27
 1.200E-04 20 Mitotic sister chromatid segregation
Reproduction
 5.123E-09 34 Cellular process involved in reproduction in multicellular organism 1.935E-04 32
 3.552E-03 38 Developmental process involved in reproduction
 2.571E-10 45 Gamete generation 6.086E-07 47
 4.132E-04 22 Germ cell development
 5.576E-09 36 Male gamete generation 1.275E-07 40
 2.764E-10 50 Multicellular organism reproduction 1.636E-06 52
 1.820E-10 50 Multicellular organismal reproductive process 1.114E-06 52
 1.069E-08 51 Multiorganism reproductive process 7.508E-06 55
 4.636E-07 32 Spermatogenesis 1.644E-05 35
 1.714E-09 70 Reproduction 2.358E-10 87
 1.562E-09 70 Reproductive process 2.107E-10 87
 6.031E-09 48 Sexual reproduction 6.886E-06 51
Cell movement
Axonemal dynein complex assembly 3.776E-05 10
Axoneme assembly 5.973E-05 13
Cilium assembly 1.831E-09 42
Cilium movement 1.554E-06 14
Cilium organization 9.106E-11 45
Epithelial cilium movement 4.190E-02 6
Flagellated sperm motility 7.720E-07 17
Inner dynein arm assembly 1.844E-03 7
Microtubule bundle formation 3.974E-05 16
 6.823E-03 36 Microtubule cytoskeleton organization 3.954E-07 54
Microtubule-based movement 3.812E-03 28
 4.303E-02 44 Microtubule-based process 1.890E-09 74
Sperm motility 1.223E-07 18
Other
 3.605E-02 78 Cellular response to stress
 2.691E-02 44 Protein modification by small protein conjugation
 2.713E-03 53 Protein modification by small protein conjugation or removal
 9.280E-03 43 Protein ubiquitination
Cellular component
Cell part
 7.530E-08 503 Cell 5.626E-13 674
 5.872E-08 500 Cell part 1.748E-13 671
 4.979E-02 3 Central element
 1.190E-02 35 Centrosome 1.280E-04 48
 1.231E-02 75 Cytoskeletal part 1.813E-08 115
 3.181E-02 87 Cytoskeleton 1.599E-06 128
Nucleus
 2.065E-05 39 Nuclear chromosome 6.220E-07 50
 5.719E-04 34 Nuclear chromosome part 2.581E-05 44
 7.360E-07 174 Nuclear lumen 1.072E-06 219
 1.470E-10 202 Nuclear part 2.306E-11 257
Nuclear ubiquitin ligase complex 2.946E-03 10
 6.971E-05 137 Nucleoplasm 1.660E-06 180
 3.601E-11 274 Nucleus 2.304E-10 345
Chromosome
 3.987E-06 57 Chromosomal part 1.956E-08 75
 9.117E-05 26 Chromosomal region 5.403E-05 31
 1.363E-06 62 Chromosome 8.355E-09 81
 1.553E-02 16 Chromosome. Centromeric region 1.121E-02 19
 1.506E-08 23 Condensed chromosome 1.658E-05 22
Condensed chromosome kinetochore 2.874E-02 7
 1.585E-02 5 Condensed chromosome outer kinetochore
 2.605E-06 15 Condensed nuclear chromosome 5.989E-04 14
Centriole 2.667E-02 14
Kinetochore 2.477E-02 15
 2.749E-02 22 Spindle 5.091E-03 28
Microtubule/cilium
9 + 2 Motile cilium 2.322E-05 15
Axoneme 5.710E-03 13
Ciliary part 2.657E-04 37
Ciliary plasm 5.710E-03 13
Cilium 3.269E-07 50
Cytoplasm 5.600E-03 425
 3.301E-02 22 Microtubule 2.308E-03 29
 6.755E-06 69 Microtubule cytoskeleton 1.072E-11 100
 2.763E-04 46 Microtubule organizing center 5.210E-07 63
Microtubule organizing center part 1.342E-03 20
Motile cilium 1.848E-07 22
Sperm
Sperm flagellum 5.648E-05 14
Sperm part 1.202E-04 18
Molecular function
Binding
 1.472E-03 91 Adenyl nucleotide binding 3.998E-04 118
 1.267E-03 91 Adenyl ribonucleotide binding 3.326E-04 118
 6.819E-04 90 ATP binding 2.280E-04 116
Chromatin binding 3.349E-02 32
 3.486E-02 4 DNA replication origin binding
 9.735E-04 97 Drug binding 1.939E-03 122
 2.279E-02 210 Heterocyclic compound binding 3.194E-02 274
 3.857E-02 110 Nucleoside phosphate binding
 3.857E-02 110 Nucleotide binding
 2.126E-02 212 Organic cyclic compound binding 3.689E-02 276
 3.246E-02 101 Purine nucleotide binding 1.953E-02 131
 1.411E-02 100 Purine ribonucleoside triphosphate binding 9.773E-03 129
 2.655E-02 101 Purine ribonucleotide binding 1.535E-02 131
 3.637E-02 101 Ribonucleotide binding 1.449E-02 132
 4.831E-02 23 Tubulin binding 4.722E-02 28
Activity
 3.020E-02 246 Catalytic activity 1.903E-02 325
 9.752E-04 19 Catalytic activity. Acting on DNA 1.142E-04 24
 2.636E-02 10 Exonuclease activity