Table 2.
Gene ontology analysis of the differentially expressed genes (DEGs) identified in the testis compared with those in the epididymis and ductus deferens.
|
P value |
No DEGs |
Gene onthology |
P value |
No DEGs |
|---|---|---|---|---|
| Testis vs. epididymis | Testis vs. ductus deferens | |||
| Biological process | ||||
| Cell cycle | ||||
| 1.690E-13 | 96 | Cell cycle | 1.764E-11 | 112 |
| 3.135E-13 | 82 | Cell cycle process | 1.562E-10 | 93 |
| 1.726E-08 | 72 | Chromosome organization | 5.773E-07 | 84 |
| 2.750E-09 | 62 | DNA metabolic process | 9.569E-07 | 69 |
| 6.606E-14 | 43 | Chromosome segregation | 1.414E-10 | 45 |
| 4.458E-14 | 47 | Nuclear division | 5.553E-08 | 45 |
| 8.737E-10 | 34 | Nuclear chromosome segregation | 1.226E-05 | 33 |
| 9.497E-03 | 32 | DNA repair | 3.965E-03 | 40 |
| 3.673E-03 | 29 | Cell cycle phase transition | 1.064E-02 | 34 |
| 3.344E-05 | 25 | DNA replication | 3.999E-08 | 34 |
| 4.722E-05 | 23 | Sister chromatid segregation | 9.632E-03 | 23 |
| 4.585E-03 | 16 | DNA-dependent DNA replication | 3.157E-03 | 19 |
| 8.777E-07 | 13 | Homologous chromosome segregation | ||
| 4.123E-02 | 11 | Chromosome separation | ||
| 1.009E-03 | 8 | DNA replication initiation | ||
| Meiosis | ||||
| 1.608E-05 | 13 | Chromosome organization involved in meiotic cell cycle | 3.059E-02 | 11 |
| 6.448E-05 | 11 | Male meiotic nuclear division | 1.276E-02 | 10 |
| 4.985E-07 | 16 | Meiosis I | ||
| 7.445E-07 | 16 | Meiosis I cell cycle process | ||
| 1.662E-12 | 29 | Meiotic cell cycle | 8.020E-07 | 26 |
| 5.564E-11 | 26 | Meiotic cell cycle process | 1.145E-05 | 23 |
| 1.588E-06 | 15 | Meiotic chromosome segregation | 3.031E-02 | 12 |
| 2.091E-11 | 25 | Meiotic nuclear division | 5.162E-06 | 22 |
| Mitosis | ||||
| 7.940E-08 | 57 | Mitotic cell cycle | 8.212E-08 | 69 |
| 9.456E-03 | 26 | Mitotic cell cycle phase transition | ||
| 1.875E-06 | 48 | Mitotic cell cycle process | 5.440E-06 | 57 |
| 4.073E-05 | 27 | Mitotic nuclear division | 1.531E-02 | 27 |
| 1.200E-04 | 20 | Mitotic sister chromatid segregation | ||
| Reproduction | ||||
| 5.123E-09 | 34 | Cellular process involved in reproduction in multicellular organism | 1.935E-04 | 32 |
| 3.552E-03 | 38 | Developmental process involved in reproduction | ||
| 2.571E-10 | 45 | Gamete generation | 6.086E-07 | 47 |
| 4.132E-04 | 22 | Germ cell development | ||
| 5.576E-09 | 36 | Male gamete generation | 1.275E-07 | 40 |
| 2.764E-10 | 50 | Multicellular organism reproduction | 1.636E-06 | 52 |
| 1.820E-10 | 50 | Multicellular organismal reproductive process | 1.114E-06 | 52 |
| 1.069E-08 | 51 | Multiorganism reproductive process | 7.508E-06 | 55 |
| 4.636E-07 | 32 | Spermatogenesis | 1.644E-05 | 35 |
| 1.714E-09 | 70 | Reproduction | 2.358E-10 | 87 |
| 1.562E-09 | 70 | Reproductive process | 2.107E-10 | 87 |
| 6.031E-09 | 48 | Sexual reproduction | 6.886E-06 | 51 |
| Cell movement | ||||
| Axonemal dynein complex assembly | 3.776E-05 | 10 | ||
| Axoneme assembly | 5.973E-05 | 13 | ||
| Cilium assembly | 1.831E-09 | 42 | ||
| Cilium movement | 1.554E-06 | 14 | ||
| Cilium organization | 9.106E-11 | 45 | ||
| Epithelial cilium movement | 4.190E-02 | 6 | ||
| Flagellated sperm motility | 7.720E-07 | 17 | ||
| Inner dynein arm assembly | 1.844E-03 | 7 | ||
| Microtubule bundle formation | 3.974E-05 | 16 | ||
| 6.823E-03 | 36 | Microtubule cytoskeleton organization | 3.954E-07 | 54 |
| Microtubule-based movement | 3.812E-03 | 28 | ||
| 4.303E-02 | 44 | Microtubule-based process | 1.890E-09 | 74 |
| Sperm motility | 1.223E-07 | 18 | ||
| Other | ||||
| 3.605E-02 | 78 | Cellular response to stress | ||
| 2.691E-02 | 44 | Protein modification by small protein conjugation | ||
| 2.713E-03 | 53 | Protein modification by small protein conjugation or removal | ||
| 9.280E-03 | 43 | Protein ubiquitination | ||
| Cellular component | ||||
| Cell part | ||||
| 7.530E-08 | 503 | Cell | 5.626E-13 | 674 |
| 5.872E-08 | 500 | Cell part | 1.748E-13 | 671 |
| 4.979E-02 | 3 | Central element | ||
| 1.190E-02 | 35 | Centrosome | 1.280E-04 | 48 |
| 1.231E-02 | 75 | Cytoskeletal part | 1.813E-08 | 115 |
| 3.181E-02 | 87 | Cytoskeleton | 1.599E-06 | 128 |
| Nucleus | ||||
| 2.065E-05 | 39 | Nuclear chromosome | 6.220E-07 | 50 |
| 5.719E-04 | 34 | Nuclear chromosome part | 2.581E-05 | 44 |
| 7.360E-07 | 174 | Nuclear lumen | 1.072E-06 | 219 |
| 1.470E-10 | 202 | Nuclear part | 2.306E-11 | 257 |
| Nuclear ubiquitin ligase complex | 2.946E-03 | 10 | ||
| 6.971E-05 | 137 | Nucleoplasm | 1.660E-06 | 180 |
| 3.601E-11 | 274 | Nucleus | 2.304E-10 | 345 |
| Chromosome | ||||
| 3.987E-06 | 57 | Chromosomal part | 1.956E-08 | 75 |
| 9.117E-05 | 26 | Chromosomal region | 5.403E-05 | 31 |
| 1.363E-06 | 62 | Chromosome | 8.355E-09 | 81 |
| 1.553E-02 | 16 | Chromosome. Centromeric region | 1.121E-02 | 19 |
| 1.506E-08 | 23 | Condensed chromosome | 1.658E-05 | 22 |
| Condensed chromosome kinetochore | 2.874E-02 | 7 | ||
| 1.585E-02 | 5 | Condensed chromosome outer kinetochore | ||
| 2.605E-06 | 15 | Condensed nuclear chromosome | 5.989E-04 | 14 |
| Centriole | 2.667E-02 | 14 | ||
| Kinetochore | 2.477E-02 | 15 | ||
| 2.749E-02 | 22 | Spindle | 5.091E-03 | 28 |
| Microtubule/cilium | ||||
| 9 + 2 Motile cilium | 2.322E-05 | 15 | ||
| Axoneme | 5.710E-03 | 13 | ||
| Ciliary part | 2.657E-04 | 37 | ||
| Ciliary plasm | 5.710E-03 | 13 | ||
| Cilium | 3.269E-07 | 50 | ||
| Cytoplasm | 5.600E-03 | 425 | ||
| 3.301E-02 | 22 | Microtubule | 2.308E-03 | 29 |
| 6.755E-06 | 69 | Microtubule cytoskeleton | 1.072E-11 | 100 |
| 2.763E-04 | 46 | Microtubule organizing center | 5.210E-07 | 63 |
| Microtubule organizing center part | 1.342E-03 | 20 | ||
| Motile cilium | 1.848E-07 | 22 | ||
| Sperm | ||||
| Sperm flagellum | 5.648E-05 | 14 | ||
| Sperm part | 1.202E-04 | 18 | ||
| Molecular function | ||||
| Binding | ||||
| 1.472E-03 | 91 | Adenyl nucleotide binding | 3.998E-04 | 118 |
| 1.267E-03 | 91 | Adenyl ribonucleotide binding | 3.326E-04 | 118 |
| 6.819E-04 | 90 | ATP binding | 2.280E-04 | 116 |
| Chromatin binding | 3.349E-02 | 32 | ||
| 3.486E-02 | 4 | DNA replication origin binding | ||
| 9.735E-04 | 97 | Drug binding | 1.939E-03 | 122 |
| 2.279E-02 | 210 | Heterocyclic compound binding | 3.194E-02 | 274 |
| 3.857E-02 | 110 | Nucleoside phosphate binding | ||
| 3.857E-02 | 110 | Nucleotide binding | ||
| 2.126E-02 | 212 | Organic cyclic compound binding | 3.689E-02 | 276 |
| 3.246E-02 | 101 | Purine nucleotide binding | 1.953E-02 | 131 |
| 1.411E-02 | 100 | Purine ribonucleoside triphosphate binding | 9.773E-03 | 129 |
| 2.655E-02 | 101 | Purine ribonucleotide binding | 1.535E-02 | 131 |
| 3.637E-02 | 101 | Ribonucleotide binding | 1.449E-02 | 132 |
| 4.831E-02 | 23 | Tubulin binding | 4.722E-02 | 28 |
| Activity | ||||
| 3.020E-02 | 246 | Catalytic activity | 1.903E-02 | 325 |
| 9.752E-04 | 19 | Catalytic activity. Acting on DNA | 1.142E-04 | 24 |
| 2.636E-02 | 10 | Exonuclease activity | ||