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. 2020 Oct 30;2020:8894257. doi: 10.1155/2020/8894257

Figure 4.

Figure 4

Effects of JPYS on the proteins expression of HIF-2α and EPO in rats. (a) Representative Western blot images of HIF-2α and EPO in the kidney. (b) Kidney proteins expression of HIF-2α and EPO relative to GAPDH. (c) Representative Western blot images of HIF-2α and EPO in the liver. (d) Liver proteins expression of HIF-2α and EPO relative to GAPDH. The results were presented as the means ± standard deviations (n = 3; ∗∗P < 0.01 compared with the sham group; #P < 0.05, ##P < 0.01 and ###P < 0.001 compared with the RA group). JPYS, Jian-Pi-Yi-Shen formula; HIF-2α, hypoxia inducible factor-2α; EPO, erythropoietin; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; RA, renal anemia; LJPYS, low dose Jian-Pi-Yi-Shen (1.5 g/kg/d); HJPYS, high dose Jian-Pi-Yi-Shen (6.0 g/kg/d).