Table 5.
Cox proportional hazards model analysis of risk factors for the duration of viral positivity in the 115 patients with COVID19.
| Variables | n (%) | T1 |
T2 |
||||||
|---|---|---|---|---|---|---|---|---|---|
| Log Rank |
Multivariate analysis |
Log Rank |
Multivariate analysis |
||||||
| χ2 | p value | HR (95% CI) | p value | χ2 | p value | HR (95% CI) | p value | ||
| Age cut-off mean (y) <60y ≥60y |
48 (41.7) 67 (58.3) |
0.337 | 0.561 | 0.140 | 0.708 | ||||
| Sex male female |
61 (53.0) 54 (47.0) |
2.45 | 0.117 | 0.903 | 3.741 | 0.053 | 0.924 | ||
| Fever (symptom) yes no |
93 (80.9) 22 (19.1) |
9.081 | 0.003 | 0.286 | 9.151 | 0.002 | 0.297 | ||
| Comorbidities none diabetes |
42 (36.5) 33 (28.7) |
4.136 | 0.042 | 0.311 | 4.925 | 0.026 | 0.259 | ||
| Severity of the disease common severe critical |
6 (5.2) 101 (87.8) 8 (7.0) |
6.464 | 0.039 | 0.132 | 7.363 | 0.025 | 0.228 | ||
| Grades of lung lesions on chest CT Ⅰ Ⅱ Ⅲ Ⅳ |
34 (29.6) 29 (25.2) 32 (27.8) 20 (17.4) |
0.060 | 0.807 | 0.129 | 0.720 | ||||
| WBC [(3.5–9.5) × 109/L] <3.5 × 109/L (3.5–9.5) × 109/L >9.5 × 109/L |
11 (9.6) 101 (87.8) 3 (2.6) |
1.515 | 0.218 | 0.774 | 0.379 | ||||
| N [(1.8–6.3) × 109/L] <1.8 × 109/L (1.8–6.3) × 109/L >6.3 × 109/L |
6 (5.2) 93 (80.9) 16 (13.9) |
1.921 | 0.166 | 1.280 | 0.258 | ||||
| L [ (1.1–3.2) × 109/L] <1.1 × 109/L ≥1.1 × 109/L |
50 (43.5) 65 (56.5) |
0.001 | 0.971 | 0.008 | 0.931 | ||||
| Hb (130–175 g/L) <130 g/L ≥130 g/L |
67 (58.3) 48 (41.7) |
0.840 | 0.359 | 2.095 | 0.148 | 0.907 | |||
| AST (8–40 U/L) ≤40 U/L >40 U/L |
90 (78.3) 25 (21.7) |
0.566 | 0.444 | 0.434 | 0.510 | ||||
| ALT (5–40 U/L) ≤40 U/L >40 U/L |
66 (57.4) 49 (42.6) |
6.390 | 0.011 | 1.957 (1.159–3.303) | 0.012 | 7.339 | 0.007 | 2.164 (1.276–3.670) | 0.004 |
| LDH (109–245 U/L) ≤245 U/L >245 U/L |
72 (62.6) 43 (37.4) |
0.465 | 0.495 | 0.465 | 0.495 | ||||
| PA (150–400 mg/L) <150 mg/L ≥150 mg/L |
47 (40.9) 68 (59.1) |
0.453 | 0.501 | 0.472 | 0.492 | ||||
| ALB (33–55 g/L) <33 g/L ≥33 g/L |
72 (62.6) 43 (37.4) |
2.849 | 0.091 | 0.396 | 2.744 | 0.098 | 0.423 | ||
| ALB/GLB (1.5–2.5) <1.5 ≥1.5 |
91 (79.1) 24 (20.9) |
0.960 | 0.327 | 1.274 | 0.259 | ||||
| Uric acid (208–428 μmol/L) ≤428 μmol/L >428 μmol/L |
104 (90.4) 11 (9.6) |
0.536 | 0.464 | 0.223 | 0.637 | ||||
| GLU (3.9–6.1 mmol/L) 3.9–6.1 mmol/L >6.1 mmol/L |
47 (40.9) 68 (59.1) |
4.071 | 0.044 | 1.731 (1.018–2.945) | 0.043 | 5.780 | 0.016 | 2.064 (1.195–3.566) | 0.009 |
| TG (0–1.7 mmol/L) 0–1.7 mmol/L >1.7 mmol/L |
76 (66.1) 39 (33.9) |
1.405 | 0.236 | 1.179 | 0.278 | ||||
| HDLC (1.04–1.66 mmol/L) <1.04 mmol/L ≥1.04 mmol/L |
75 (65.2) 40 (34.8) |
4.728 | 0.030 | 0.526 (0.307–0.904) | 0.020 | 5.419 | 0.020 | 0.527 (0.307–0.907) | 0.021 |
| LDLC (0–3.12 mmol/L) 0–3.12 mmol/L >3.12 mmol/L |
84 (73.0) 31 (27.0) |
0.381 | 0.537 | 0.466 | 0.495 | ||||
| CRP (0–8 mg/L) a 0–8 mg/L >8 mg/L |
54 (48.6) 57 (51.4) |
2.037 | 0.154 | 1.844 | 0.174 | ||||
| HCY (0–20 μmol/L)b 0–20 μmol/L >20 μmol/L |
88 (95.7) 4 (4.3) |
0.730 | 0.393 | 0.567 | 0.451 | ||||
| CycC (0.55–1.05 mg/L)c ≤1.05 mg/L >1.05 mg/L |
93 (84.5) 17 (15.5) |
0.243 | 0.622 | 0.236 | 0.624 | ||||
a
Data missing in 4 cases.
b
Data missing in 23 cases.
c
Data missing in 5 cases.