Table 3.

Changes of electrolytes, acid-base status, and glucose from baseline until 6 hours (n = 42)

Hour	0 (n = 42)	2 (n = 40)a	4 (n = 24)a	6 (n = 21)a	P value
pH	7.35 ± 0.08	7.37 ± 0.07b	7.36 ± 0.08c	7.38 ± 0.08d	0.002b
PCO2 (kPa)	6.37 ± 1.51	6.18 ± 1.10	6.66 ± 1.70	6.46 ± 1.28	0.75
Na (mmol/L)	141.31 ± 5.17	141.59 ± 4.07	140.84 ± 3.65	141.13 ± 2.92	0.65
K (mmol/L)	5.21 ± 0.63	4.80 ± 0.51b	4.50 ± 0.38c	4.33 ± 0.37d	<0.001
Cloride (mmol/L)	101.38 ± 3.00	101.22 ± 2.84	100.69 ± 2.76	99.66 ± 2.40d	<0.001
HCO3 (mmol/L)	25.49 ± 3.10	25.31 ± 5.01	27.44 ± 3.02c	27.46 ± 3.10d	0.02
BE	−0.33 ± 3.26	0.56 ± 3.42b	1.70 ± 3.21c	2.03 ± 3.31d	<0.001
Lactate (mmol/L)	1.32 ± 0.50	1.38 ± 0.38	1.38 ± 0.46	1.34 ± 0.42	0.84
iCa (mmol/L)	1.13 ± 0.09	1.12 ± 0.06	1.11 ± 0.07	1.12 ± 0.04	0.48
Glucose (mmol/L)	9.84 ± 2.90	9.25 ± 3.11	8.60 ± 2.44	8.50 ± 2.14	0.17
Mg (mmol/L)	1.22 ± 0.22	—	—	1.13 ± 0.28e	0.15

BE, base excess; iCa, ionized calcium; PCO₂, partial pressure of carbon dioxide.

Bold P values are statistically significant.

^aLaboratory data were not obtained after switching to commercial fluids.

^bP < 0.05 for time 0 vs. 2.

^cP < 0.05 for time 0 vs. 4.

^dP < 0.05 for time 0 vs. 6.

^eMagnesium was measured once daily. Therefore, the values represent the levels at 24 hours. There were no missing data for magnesium levels.