Table 1.
Thymoliposarcoma cases in the literature (UA: unavailable data; unfortunately we could not provide the full data of the third case).
Case | Age | Sex | Clinical Presentation | Size | Pathology | Treatment | Recurrence | Metastases | Follow up |
---|---|---|---|---|---|---|---|---|---|
Havlicek F [3] | 39 | F | Asymptomatic (pressure sensation) | 13 × 9.5 × 5 (650 gr.) | Well differentiated to pleomorphic | Surgical Resection | 25 years after the initial surgery (surgery + radiotherapy) | 4 years after recurrence (radiotherapy) | 32 years |
Jones H [7] | 1 | M | Weight loss, malaise, night sweats, shoulder pain, chest infections | 450 gr. | Thymosarcoma with liposarcomatous differentiated | Surgical Resection | 21 months of initial surgery (treated with radiotherapy) | Nodular Metastasis | 21 months |
Cristallini EG [8] | UA | UA | UA | UA | UA | UA | UA | UA | UA |
Klimstra DS [6] | 72 | F | Asymptomatic | No Data | Well-Differentiated | Surgical Resection (after 2 years) | – | – | 6 months |
Sekine Y [1] | 77 | F | Asymptomatic | 9 × 8.5 × 5.4 cm | Well- differentiated | Surgical Resection + adjuvant radiotherapy | – | – | 29 months |
Howling SJ [9] | 70 | F | Non-productive cough | 12 cm | Lipoblastic with undifferentiated myxoid pattern | Surgical Resection | – | – | No Data |
Sung MT [4] | 36 | M | Asymptomatic | 12.5 × 11 × 5.3 cm | Well-differentiated | Surgical Resection | 4 years after surgery (13.2 × 7.5 × 4.4 cm, surgery and radiotherapy) | – | 10 months after recurrence |
Sivaraman A [10] | 55 | M | Non-specific chest pain | 30 × 12 × 12 (5120 gr.) | Pleomorphic | Surgical with Radiotherapy | – | – | 3 months |
Mansuet-Lupo A [2] | 63 | M | Dyspnea, Weight loss | 11 cm | Dedifferentiated | chemotherapy (doxorubicin + ifosphamode) | – | Costolateral lung micronodules | No Data |
Hosaka Y [11] | 63 | M | Asymptomatic | 8.3 × 5.3 × 8.2 cm | Dedifferentiated | Surgical Resection | – | – | 1 year |
Alhames S (our case) | 46 | M | Fatigue, Dyspnea, Non-specific chest pain | 35 × 25 (5145 gr.) | Well-differentiated | Surgical Resection | – | – | 6 months |