Table 2.

Nurses’ Health Studies: Relative Risk of UI Progression from Mild/Moderate to Severe UI, According to Vitamin D Intake from Food and Supplements

NURSES’ HEALTH STUDY
Vitamin D intake (IU)	Cases	Person-years	Age-adjusted RR (95% CI)	Multi-variable adjusted RR‡
0–<200	627	12,189	1.0 (ref)	1.0 (ref)
200–<400	672	12,120	1.08 (0.97, 1.21)	1.10 (0.99, 1.23)
400–<600	1163	21,805	1.05 (0.95, 1.16)	1.09 (0.99, 1.21)
600–<800	1031	19,964	1.00 (0.91, 1.11)	1.05 (0.95, 1.16)
800–<1000	558	10,635	1.03 (0.92, 1.16)	1.10 (0.98, 1.24)
1000+	802	15,731	1.02 (0.91, 1.14)	1.10 (0.99, 1.23)
				p-trend=0.3
NURSES’ HEALTH STUDY II
Vitamin D intake (IU)	Cases	Person-years	Age-adjusted RR (95% CI)	Multi-variable adjusted RR‡
0–<200	296	16,375	1.0 (ref)	1.0 (ref)
200–<400	265	16,275	0.87 (0.74, 1.03)	0.93 (0.79, 1.11)
400–<600	301	16,916	0.95 (0.81, 1.12)	1.00 (0.85, 1.18)
600–<800	265	14,018	1.00 (0.85, 1.19)	1.08 (0.91, 1.28)
800–<1000	125	7,283	0.89 (0.72, 1.10)	0.98 (0.79, 1.22)
1000+	126	8,318	0.80 (0.65, 0.99)	0.88 (0.71, 1.10)
				p-trend=0.7

^‡Multivariable models adjusted for age, body mass index, cigarette smoking, parity, use of postmenopausal hormone therapy, physical activity.