TABLE 3.
Gene enriched terms for GO and KEGG pathways
| Term | Description | No. of Genes | P‐value | FDR |
|---|---|---|---|---|
| GO: Biological process | ||||
| GO:0055114 | Oxidation‐reduction process | 54 | 4.89E‐10 | 4.08E‐06 |
| GO:0045333 | Cellular respiration | 18 | 4.17E‐09 | 1.74E‐05 |
| GO:0006091 | Generation of precursor metabolites and energy | 24 | 6.68E‐08 | 1.85E‐04 |
| GO:0015980 | Energy derivation by oxidation of organic compounds | 20 | 2.06E‐07 | 2.86E‐04 |
| GO:0007005 | Mitochondrion organization | 29 | 4.36E‐06 | 2.45E‐03 |
| GO:0008219 | Cell death | 67 | 4.42E‐06 | 2.45E‐03 |
| GO:0097190 | Apoptotic signaling pathway | 30 | 5.72E‐06 | 2.75E‐03 |
| GO:0006915 | Apoptotic process | 62 | 1.04E‐05 | 3.61E‐03 |
| GO:0012501 | Programmed cell death | 62 | 1.63E‐05 | 4.84E‐03 |
| GO:0006099 | Tricarboxylic acid cycle | 6 | 3.27E‐05 | 7.79E‐03 |
| KEGG pathways | ||||
| mmu00190 | Oxidative phosphorylation | 22 | 2.17E‐12 | 6.49E‐10 |
| mmu05012 | Parkinson disease | 21 | 7.31E‐11 | 1.09E‐08 |
| mmu05010 | Alzheimer disease | 21 | 2.91E‐09 | 2.90E‐07 |
| mmu05016 | Huntington disease | 21 | 1.88E‐08 | 1.40E‐06 |
| mmu01100 | Metabolic pathways | 61 | 8.03E‐07 | 4.80E‐05 |
| mmu04932 | Non‐alcoholic fatty liver disease (NAFLD) | 16 | 1.60E‐06 | 7.98E‐05 |
| mmu01200 | Carbon metabolism | 13 | 8.85E‐06 | 3.78E‐04 |
| mmu00020 | Citrate cycle (TCA cycle) | 6 | 1.34E‐04 | 5.02E‐03 |
| mmu04142 | Lysosome | 10 | 1.23E‐03 | 4.09E‐02 |
| mmu00010 | Glycolysis/Gluconeogenesis | 7 | 1.39E‐03 | 4.16E‐02 |