Table 3.
Prognostic analysis of the advanced‐stage case cohort of patients with mucoepidermoid carcinoma (N = 84)
| Factor | N | Overall survival | Disease‐free survival | ||||
|---|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | ||
| Age (y) | |||||||
| <60 | 47 | 1.00 | 1.00 | ||||
| ≥60 | 37 | 1.72 | 0.52‐5.65 | .370 | 2.77 | 1.15‐6.66 | .018 |
| Sex | |||||||
| Male | 43 | 1.00 | 1.00 | ||||
| Female | 38 | 0.34 | 0.09‐1.29 | .093 | 1.23 | 0.53‐2.86 | .622 |
| Primary site | |||||||
| Major gland | 66 | 1.00 | 1.00 | ||||
| Minor gland | 18 | 4.41 | 1.34‐14.49 | .016 | 3.44 | 1.48‐7.99 | .005 |
| CRTC1/3‐MAML2 | |||||||
| Positive | 38 | 1.00 | 1.00 | ||||
| Negative | 46 | 3.68*10^9 | NA | <.001 | 1.86 | 0.75‐4.57 | .161 |
| pT classification | |||||||
| pT1/2 | 11 | 1.00 | 1.00 | ||||
| pT3/4 | 73 | 0.84 | 0.18‐3.92 | .828 | 0.89 | 0.30‐2.68 | .851 |
| pN classification | |||||||
| pN0 | 51 | 1.00 | 1.00 | ||||
| pN1‐3 | 33 | 4.96 | 1.31‐18.74 | .010 | 2.58 | 1.10‐6.05 | .027 |
| Tumor grade | |||||||
| Low | 56 | 1.00 | 1.00 | ||||
| Intermediate/high | 28 | 2.08 | 0.63‐6.84 | .235 | 2.15 | 0.92‐4.99 | .081 |
| Surgical margin | |||||||
| Negative | 53 | 1.00 | 1.00 | ||||
| Close/positive | 31 | 1.29 | 0.37‐4.42 | .688 | 1.52 | 0.64‐3.58 | .341 |
| Neck dissection | |||||||
| Yes | 54 | 1.00 | 1.00 | ||||
| No | 30 | 0.36 | 0.07‐1.70 | .160 | 1.09 | 0.46‐2.62 | .832 |
| Postoperative therapy | |||||||
| Not performed | 61 | 1.00 | 1.00 | ||||
| Performed | 23 | 2.37 | 0.72‐7.78 | .164 | 1.32 | 0.53‐3.23 | .551 |
Follow‐up median, 39.5 mo (range, 3‐320).
Abbreviations: CI, confidence interval; HR, hazard ratio; NA, not available.