FIGURE 1.

PICSAR is upregulated in hepatocellular carcinoma (HCC) and is associated with poor prognosis. A, The ENCORI platform database indicated that the expression of PICSAR was prominently higher in HCC tissues compared with normal liver tissues. B, Real‐time PCR data from our patient’s cohort revealed that PICSAR was significantly upregulated in HCC tissues compared to normal tissues. C, PICSAR expression in human normal hepatocyte cell line L02 and HCC cell lines was examined using quantitative RT‐PCR. D, Kaplan‐Meier survival curves of overall survival and disease‐free survival in our patients’ cohort. Patients were assigned into two subgroups according to the median expression of PICSAR. E, The ENCORI platform database showed that high PICSAR expression also indicated poor survival of HCC patients. *P < .05, **P < .01, ***P < .001