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. 2020 Nov 6;10:19257. doi: 10.1038/s41598-020-76243-7

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Healing pattern of the wounded skin over time. Skin wound healing model (a). Blood flow evaluation in control and PBM-treated wounds at baseline, day 3, and day 6 post-surgery. Red colors below the bars represent greater blood flow, while turbulent flow is represented in yellow or green (b). Remaining wound area (%) for total closure from day 2 until day 7 (c). Macroscopic appearance of control and PBM-treated wounds at days 3 and 7. Note that PBM-treated wounds are humid and with less rolled edges—3rd day; smaller, more uniformly healed and thinner eschar than the control at day 7 (d). Data are shown as the mean ± SD, n = 5 for each group. N.S. = non-significant. Scale bar = 5 mm.