Table 1.
The distributions of demographic and clinicopathologic characteristics of colorectal cancer patients in the two cohorts.
| Discovery cohort | Validation cohort | ||
|---|---|---|---|
| (158/499)* | (72/315)* | P | |
| Age | <0.001 | ||
| ≤ 60 year | 195 (39.1%) | 180 (57.1%) | |
| > 60 year | 304 (60.9%) | 135 (42.9%) | |
| Sex | 0.914 | ||
| Male | 301 (60.3%) | 188 (59.7%) | |
| Female | 198 (39.7%) | 127 (40.3%) | |
| T-stage | <0.001 | ||
| T1 | 14 (2.8%) | 0 (0%) | |
| T2 | 76 (15.2%) | 0 (0%) | |
| T3 | 360 (72.1%) | 261 (82.9%) | |
| T4 | 49 (9.8%) | 54 (17.1%) | |
| N-stage | 0.039 | ||
| N0 | 264 (52.9%) | 141 (44.8%) | |
| N1 | 145 (29.1%) | 117 (37.1%) | |
| N2 | 90 (18.0%) | 57 (18.1%) | |
| Stage | <0.001 | ||
| I | 71 (14.2%) | 0 (0%) | |
| II | 191 (38.3%) | 142 (45.1%) | |
| III | 228 (45.7%) | 173 (54.9%) | |
| IV | 9 (1.8%) | 0 (0%) | |
| Tumour site | 0.147 | ||
| Colon | 287 (57.5%) | 164 (52.1%) | |
| Rectum | 212 (42.5%) | 151 (47.9%) | |
| Median follow-up time (95% CI) | 89 (79-96) | 51 (50-53) | |
| 1-year survival rate (95% CI) | 93.2% (91.0%-95.4%) | 96.8% (94.9%-98.8%) | 0.038 |
| 3-year survival rate (95% CI) | 80.0% (76.5%-83.6%) | 83.5% (79.5%-87.7%) | 0.243 |
| 5-year survival rate (95% CI) | 74.3% (70.6%-78.3%) | 72.5% (66.1%-79.5%) | 0.590 |
Note: P value was performed by Kruskal–Wallis or χ2 test where appropriate.
⁎
Numbers in parentheses are number of events/total number of patients.
Abbreviation: CI, confidence interval.