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. 2020 Oct 8;27:100555. doi: 10.1016/j.eclinm.2020.100555

Table 3.

Summary of correlations between maternal haematological indices and neonatal iron and haematological indices.

Mother Neonate Number of Studies and References Pooled weighted mean correlation coefficient (95% CI)(Schmidt-Hunter)
Hb (n = 32) Ferritin 6[23,32,38,58,62,76] 0.16 (−0.12, 0.43) – Negligible
P = 0.27
Hepcidin 1[76] Not calculated
Plasma/serum iron 5 [25,54,58,64,76] 0.29 (0.04, 0.54) – Negligible
P = 0.02
sTfR 2[56,35] Not calculated
Tf Sat 3[27,64,76] 0.35 (−0.05, 0.75) – Low positive
P = 0.09
TIBC 4[25,58,64,76] −0.22 (−0.52, 0.08) – Negligible
P = 0.16
ZPP 1[64] Not calculated
Hb 32[21,[26], [27], [28], [29],32,33,35,36,38,42,43,47,49,54,57,59,[63], [64], [65]-67,70,[72], [73], [74],76,78,81,83,85,88] 0.15 (0.10, 0.20) – Negligible
P<0.0001
Ht 3[25,28,85] 0.13 (0.007, 0.25) – Negligible
P = 0.04
MCHb 2[27,38] Not calculated
MCV 3[27,38,64] 0.20 (−0.07, 0.46) – Negligible
P = 0.14
Ht (n = 13) Ferritin 2[32,58] Not calculated
Plasma/serum iron 1[58] Not calculated
sTfR 1[24] Not calculated
TIBC 1[58] Not calculated
Hb 3[28,32,85] 0.14 (0.04, 0.25) – Negligible
P = 0.01
Ht 10[28,29,34,47,65,67,70,72,73,85] 0.15 (0.06, 0.23) – Negligible
P = 0.001
MCV (n = 7) Ferritin 1[58] Not calculated
Plasma/serum iron 1 [58] Not calculated
TIBC 1 [58] Not calculated
MCV 6[33,42,47,63,65,70] 0.22 (0.10, 0.33) – Negligible
P = 0.0002
MCHb (n = 6) Ferritin 1[58] Not calculated
Plasma/serum iron 1[58] Not calculated
TIBC 1[58] Not calculated
MCHb 5[33,42,47,65,70] 0.25 (0.08, 0.43) – Negligible
P = 0.004

Hb=haemoglobin; Ht=haematocrit; MCHb=mean corpuscular haemoglobin; MCV=mean cell volume; NOS=Newcastle-Ottawa scale; sTfR=soluble/serum transferrin receptor; TIBC=total iron binding capacity; Tf=transferrin; Tf Sat=transferrin saturation; ZPP= zinc protoporphyri.