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A single-nucleotide insertion in the covR promoter confers altered hemolytic activity and CAMP activity on CNCTC10/84. (A) Schematic depiction of the covR upstream sequences of assayed strains. CovR binding sequence is underlined. (B) Hemolytic and pigmentation phenotypes of GBS strains. (C and D) Hemolytic activity (C) and CAMP activity (D) of GBS strains. OD, optical density. *, P < 0.05 versus 10/84 (n = 4, one-way analysis of variance with Dunnett’s multiple-comparison test).
