Table 2. Laboratory Studies on Initial Presentation.
Laboratory study | Median (IQR) |
---|---|
White blood cell count, /μL | 15 300 (12 300-17 900) |
Differential, median (IQR), % | |
Granulocytes | 90.3 (88.0-92.4) |
Lymphocytes | 5.7 (4.2-7.9) |
Monocytes | 2.4 (2-3.2) |
Basophils | 0.2 (0.1-0.3) |
Eosinophils | 0.3 (0.1-0.9) |
ESR, mm/h | 75 (42-100) |
CRP, mg/dL | 25.8 (18.7-30.2) |
Elevated, No./total No. (%) | |
ESRa | 25/26 (96) |
CRPb | 27/27 (100) |
ESR or CRP | 28/28 (100) |
ESR >100 mm/h | 7/26 (27) |
Procalcitonin, ng/mL | 0.3 (0.1-0.7) |
Creatinine, mg/dL | 0.85 (0.73-0.94) |
Total bilirubin, mg/dL | 1.0 (0.6-1.4) |
AST, U/L | 31 (25-37) |
ALT, U/L | 24 (18-39) |
Elevated, No./total No. (%) | |
ASTc | 6/30 (20) |
ALTd | 5/30 (17) |
AST or ALT | 7/30 (23) |
Alkaline phosphatase, U/L | 85 (72-114) |
HIV 1, 2 antigen or antibody | |
Negative, No./total No. (%) | 19/19 (100) |
BAL performed, No./total No. (%) | 24/31 (77) |
Cytologic differential, % | |
Macrophages | 53 (33-79) |
Neutrophils | 28 (12-48) |
Lymphocytes | 6 (2-12) |
Eosinophils | 0 (0-2) |
Presence of LLMs, No./total No. (%)e | 21/23 (91) |
LLMs, median (IQR), % | 52 (33-76) |
Urine drug screen, No./total No. (%) | |
Marijuana | 11/11 (100) |
Cocaine | 0/11 |
Heroin | 0/1 |
Methamphetamine | 1/11 (9) |
Narcotics | 2/11 (18) |
Benzodiazepine | 0/11 |
Methadone | 0/11 |
Buprenorphine | 0/11 |
Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; BAL, bronchoalveolar lavage; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; IQR, interquartile range; LLM, lipid-laden microphage.
SI conversion factors: To convert AST, ALT, and alkaline phosphatase to microkatals per liter, multiply by 0.0167; creatinine to micromoles per liter, multiply by 76.25; CRP to milligrams per liter, multiply by 10; total bilirubin to micromoles per liter, multiply by 17.104; and white blood cell count to ×109/μL, multiply by 0.001.
Greater than upper reference limit (20 mm/h).
Greater than upper reference limit (0.8 mg/dL).
Greater than upper reference limit (40 U/L).
Greater than upper reference limit (60 U/L).
One patient who underwent BAL did not have LLM testing performed.