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. Author manuscript; available in PMC: 2021 Apr 21.
Published in final edited form as: Nat Methods. 2020 Oct 21;17(11):1156–1166. doi: 10.1038/s41592-020-00981-9

Extended Data Fig. 4. The response of GRABDA sensors to different compounds.

Extended Data Fig. 4

a, The normalized dose-response curves for DA and NE in sensor-expressing HEK293T cells. n=3 wells with 200–800 cells/well.

b, The ΔF/F0 in sensor-expressing cells in response to the indicated compounds applied at 1 μM. n=3 wells for rDA1h in response to NE, 5-HT, Oct, Gly and L-DOPA. n=4 wells for the others. Each well contains 200-1200 cells.

Data are presented as the mean ± s.e.m..

Data replotted from Fig. 2a.