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. Author manuscript; available in PMC: 2021 Apr 21.
Published in final edited form as: Nat Methods. 2020 Oct 21;17(11):1156–1166. doi: 10.1038/s41592-020-00981-9

Extended Data Fig. 2. The sequences of GRABDA sensors and the residues related to affinity-tuning, cpRFP and cpEGFP optimization.

Extended Data Fig. 2

a,b, The sequences of rGRABDA1m (a) and GRABDA2m (b). The residues related to affinity-tuning, cpRFP (a) and cpEGFP (b) optimization are marked. T2055.54M was introduced to rDA1m and DA2m to generate rDA1h and DA2h, respectively.