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. 2020 Nov 7;12:168. doi: 10.1186/s13148-020-00961-y

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Decreased STXBP5-AS1 predicted poor prognosis in pancreatic cancer. a Kaplan–Meier’s analysis of the correlation between STXBP5-AS1 expression and the overall survival of PC patients. b Kaplan–Meier’s analysis of the correlation between STXBP5-AS1 expression and the relapse free survival of PC patients. c qRT-PCR analysis of STXBP5-AS1 expression in 60 pancreatic cancer tissues (PCT, 28 PC tissues from lymph node metastasis (LNM) patients and 32 PC tissues from lymph node metastasis-free (LNMF) patients) and respective adjacent normal tissues (ANT) (shown as 2^−ΔΔCT). d, e STXBP5-AS1 expression in pancreatic tumor tissues and normal tissues from GSE16515 and GSE15471. f STXBP5-AS1 expression in six PC cell lines (AsPC-1, SW1990, Capan-2, CFPAC-1, PANC-1 and Mia PaCa-2) and a normal human pancreatic ductal cell line (hTERT-HPNE) was determined by qRT-PCR. g qRT-PCR analysis of STXBP5-AS1 expression in Gemcitabine-resistant (GR) or parental PANC-1 and Mia PaCa-2 cells. h The expression level of STXBP5-AS1 in spheres of PANC-1 and Mia PaCa-2 cells or parental PANC-1 and Mia PaCa-2 cells was measured by qRT-PCR.*P < 0.05; **P < 0.01