Table 6.
Agreement Rate of Allele Identification by Study Participants, Calculated for Each Blood Group Allele
| Blood group system | Polymorphism* | Laboratories that performed testing, n | Results reported | Reporting errors | No call | Discrepant results | Agreement rate, % |
|---|---|---|---|---|---|---|---|
| ABO | c.1061delC | 11 | 198 | 1 | 1 | 98.99 | |
| ABO | c.526C>G | 6 | 108 | 2 | 98.15 | ||
| ABO | c.703G>A | 8 | 144 | 1 | 2 | 97.92 | |
| ABO | c.796C>A | 7 | 126 | 2 | 98.41 | ||
| ABO | c.803G>C | 12 | 216 | 2 | 99.07 | ||
| ABO | c.261delG | 12 | 216 | 1 | 2 | 98.61 | |
| MNS | c.59C>T | 24 | 432 | 3 | 1 | 99.07 | |
| MNS | c.143C>T | 27 | 486 | 100 | |||
| MNS | c.230C>T | 21 | 378 | 16 | 95.77 | ||
| MNS | c.270+5G>T | 23 | 414 | 16 | 96.14 | ||
| RH | RHD+/RHD−† | 21 | 378 | 1 | 4 | 17 | 94.18 |
| RH | 37-bp Duplicate exon 4 | 15 | 270 | 10 | 96.3 | ||
| RH | RhC/Rhc‡ | 26 | 468 | 1 | 6 | 98.5 | |
| RH | c.676G>C | 28 | 504 | 2 | 1 | 99.4 | |
| RH | c.122A>G | 18 | 324 | 100 | |||
| RH | c.106G>A | 11 | 198 | 100 | |||
| RH | c.733C>G | 21 | 378 | 1 | 2 | 99.21 | |
| RH | c.1006G>T | 20 | 360 | 4 | 98.89 | ||
| LU | c.230G>A | 25 | 450 | 1 | 3 | 1 | 98.89 |
| KEL | c.578C>T | 28 | 504 | 4 | 99.21 | ||
| KEL | c.841C>T | 25 | 450 | 100 | |||
| KEL | c.1790T>C | 21 | 378 | 100 | |||
| FY | § | 28 | 504 | 6 | 98.81 | ||
| JK | c.838G>A | 27 | 486 | 1 | 3 | 99.18 | |
| DI | c.2561C>T | 25 | 450 | 1 | 99.78 | ||
| YT | c.1057C>A | 17 | 306 | 2 | 99.35 | ||
| SC | c.169G>A | 16 | 288 | 100 | |||
| DO | c.793A>G | 27 | 486 | 3 | 99.38 | ||
| DO | c.323G>T | 22 | 396 | 1 | 99.75 | ||
| DO | c.350C>T | 22 | 396 | 2 | 2 | 98.99 | |
| CO | c.134C>T | 24 | 432 | 1 | 1 | 99.54 | |
| LW | c.299A>G | 15 | 270 | 100 | |||
| CROM | c.679G>C | 7 | 126 | 18 | 85.71 | ||
| KN | c.4681G>A | 10 | 180 | 16 | 91.11 | ||
| KN | c.4768A>G | 7 | 126 | 100 | |||
| KN | c.4801A>G | 6 | 108 | 100 | |||
| IN | c.137G>C | 5 | 90 | 100 | |||
| OK | c.274G>A | 3 | 54 | 17 | 1 | 66.67 | |
| Total | 12,078 | 64 | 34 | 85 | 98.48 |
Blank cells denote 0 events observed.
*
Nucleotide position refers to the position within the cDNA sequence (see reference sequence in Table 3).
†
Predicted by determining RHD deletion or RHD zygosity.
‡
Predicted by testing single-nucleotide polymorphism c.307T>C and 109-bp insertion within intron 2 of RHCE (NM_020485.4).
§
Predicted by testing single-nucleotide polymorphisms c.125G>A, c.265C>T, and c.−67T>C of the ACKR1 gene (NM_002036.3). The total number of results reflects reported results for RhD, RhCc, and Fy predicted phenotypes.