Figure 1.

Quantification of viral loads from mucosal swabs. A–F; All animals [four African green monkeys (AGMs) and four rhesus macaques (RMs)] had detectable viral RNA at mucosal sites, including buccal (A), nasal (B), pharyngeal (C), bronchial brush (D), and rectal swabs (F). D: No significant differences are seen in viral load between species and route of exposure (Mann-Whitney U-test). Animals with acute respiratory disease syndrome (ARDS) trend to high viral loads in bronchial brush samples. E: Viral RNA is detected in vaginal swabs from both female AGMs but not the only female RM. Circles indicate aerosol exposure; squares, multiroute exposure; gray, RMs; red, developed ARDS; purple, increased cytokines without ARDS; and blue, no cytokine increase or ARDS.