Table 1.
Species, Source, Route of Exposure, Demographic Information, and Clinical Outcome from Each Animal in the Study
| Animal | Species | Source | Age, years | Sex | Weight, kg | Exposure (dose) | Outcome |
|---|---|---|---|---|---|---|---|
| AGM1 | Chlorocebus aethiops sabaeus | Wild caught, St. Kitts | 16 | F | 4.3 | Aerosol (1 × 104 PFU) | ARDS (8 DPI) |
| AGM2 | Chlorocebus aethiops sabaeus | Wild caught, St. Kitts | 16 | F | 3.9 | Multiroute (3.61 × 106 PFU) | ARDS (22 DPI) |
| AGM3 | Chlorocebus aethiops sabaeus | Wild caught, St. Kitts | 16 | M | 6.9 | Multiroute (3.61 × 106 PFU) | Reached study end point (26 DPI) |
| AGM4 | Chlorocebus aethiops sabaeus | Wild caught, St. Kitts | 16 | M | 7.5 | Aerosol (1 × 104 PFU) | Reached study end point (24 DPI) |
| RM1 | Macaca mulatta | Born at TNPRC | 14 | M | 16.7 | Multiroute (3.61 × 106 PFU) | Reached study end point (27 DPI) |
| RM2 | Macaca mulatta | Born at TNPRC | 13 | F | 6.9 | Multiroute (3.61 × 106 PFU) | Reached study end point (27 DPI) |
| RM3 | Macaca mulatta | Born at TNPRC | 13 | M | 11.6 | Aerosol (1 × 104 PFU) | Reached study end point (28 DPI) |
| RM4 | Macaca mulatta | Born at TNPRC | 15 | M | 11 | Aerosol (1 × 104 PFU) | Reached study end point (28 DPI) |
AGM, African green monkey; ARDS, acute respiratory distress syndrome; DPI, days post infection; PFU, plaque-forming units; RM, rhesus macque; TNPRC, Tulane National Primate Research Center.