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. 2020 Sep 25;216(3):781–804. doi: 10.1534/genetics.120.303668

Table 8. Top biological process terms from GO analysis for LM.

GO term Total genes Input genes Expected Fold enrichment Raw P-value
Locomotory exploration behavior 16 1 0.02 53.6 1.96E-02
  Locomotory behavior 240 4 0.28 14.29 1.72E-04
   Behavior 685 6 0.8 7.51 1.17E-04
Positive regulation by host of viral release from host cell 5 1 0.01 >100 6.97E-03
  Positive regulation of viral release from host cell 15 1 0.02 57.17 1.85E-02
   Regulation of viral release from host cell 31 1 0.04 27.66 3.66E-02
    Regulation of locomotion 1040 7 1.21 5.77 1.47E-04
Negative regulation of cardiac muscle cell proliferation 17 2 0.02 >100 2.20E-04
 Negative regulation of cell population proliferation 684 3 0.8 3.76 4.46E-02
 Negative regulation of cardiac muscle tissue growth 29 2 0.03 59.14 5.94E-04
  Regulation of cardiac muscle tissue growth 74 2 0.09 23.18 3.53E-03
   Regulation of cardiac muscle tissue development 98 2 0.11 17.5 6.02E-03
    Regulation of striated muscle tissue development 160 2 0.19 10.72 1.52E-02
     Regulation of muscle tissue development 163 2 0.19 10.52 1.57E-02
     Regulation of muscle organ development 164 2 0.19 10.46 1.59E-02
   Regulation of heart growth 80 2 0.09 21.44 4.09E-03
    Regulation of organ growth 114 2 0.13 15.04 8.02E-03
 Negative regulation of cardiac muscle tissue development 40 2 0.05 42.88 1.09E-03
  Negative regulation of striated muscle tissue  development 64 2 0.07 26.8 2.67E-03
  Negative regulation of muscle organ development 66 2 0.08 25.99 2.83E-03
  Negative regulation of muscle tissue development 67 2 0.08 25.6 2.92E-03
 Negative regulation of heart growth 29 2 0.03 59.14 5.94E-04
Bundle of His cell-Purkinje myocyte adhesion involved in cell communication 6 1 0.01 >100 8.13E-03
 Bundle of His cell to Purkinje myocyte communication 13 1 0.02 65.96 1.62E-02
  Cell communication involved in cardiac conduction 32 1 0.04 26.8 3.78E-02
   Multicellular organismal signaling 109 2 0.13 15.73 7.37E-03
 Cardiac muscle cell-cardiac muscle cell adhesion 7 1 0.01 >100 9.28E-03
  Cell-cell adhesion 389 3 0.45 6.61 1.04E-02
   Cell adhesion 789 6 0.92 6.52 2.50E-04
    Biological adhesion 799 6 0.93 6.44 2.68E-04
Negative regulation of cellular extravasation 8 1 0.01 >100 1.04E-02
 Negative regulation of leukocyte migration 41 2 0.05 41.83 1.14E-03
  Regulation of leukocyte migration 209 2 0.24 8.21 2.49E-02
   Regulation of cell migration 912 5 1.06 4.7 3.71E-03
    Regulation of cell motility 963 5 1.12 4.45 4.67E-03
 Negative regulation of cell migration 276 4 0.32 12.43 2.91E-04
  Negative regulation of cell motility 289 4 0.34 11.87 3.46E-04
   Negative regulation of cellular component   movement 323 4 0.38 10.62 5.24E-04
Definitive hemopoiesis 21 2 0.02 81.67 3.25E-04
a

Within groups of GO terms, items are listed in order of increasing generality.