Figure 4.
EEG delta and theta power are decreased in Tfap2b+/− mice. (A) EEG power spectra in NREMS. (B) NREMS delta power (1–4 Hz), two-way ANOVA followed by Sidak’s multiple comparisons test, the main effect of genotype, F (1,264) = 13.68, ***P = 0.0003. (C) EEG power spectra in REMS. (D) REMS theta power (6–10 Hz), two-way ANOVA followed by Sidak’s multiple comparisons test, the main effect of genotype, F (1,264) = 5.525, *P = 0.0195. (E) EEG power spectra during wakefulness. (F) Wake power analysis (0.5–4 Hz), two-way ANOVA followed by Sidak’s multiple comparisons test, the main effect of genotype, F (1,264) = 9.126, **P = 0.0028. All data are shown as the mean ± SEM, n = 7 for Tfap2b+/+, n = 6 for Tfap2b+/−. P values for 1–25 Hz were calculated using Wilcoxon two-sided signed-rank test, ****P < 0.0001. All data are shown as the mean ± SEM.