Table 2.
Spearman rank order correlations Highlighted correlations are significant at p < 0.05. r = 0.6 | |||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Overall | Control | Model 1 | Model 2 | ||||||||||||||
MMEDWB | MMEDPRP | TMEDWB | TMEDPRP | MCF7 Overall | T47D Overall | MTAMWB | MTAMPRP | TTAMWB | TTAMPRP | MCF7 Overall | T47D Overall | WBTAMM | PRPTAMM | WBTAMT | PRPTAMT | ||
Thrombin generation | |||||||||||||||||
CD62P IPA | − 0.075 | − 0.314 | 0.0857 | − 0.028 | 0.257 | − 0.242* | 0.1319 | − 0.2 | 0.7714 | 0.3 | 0.3142 | − 0.24795* | − 0.06761 | − 0.6572 | − 0.486 | − 0.579 | 0.4 |
CD63 IPA | − 0.047 | − 0.314 | 0.0285 | 0.314 | 0.428 | − 0.195 | 0.1018 | − 0.429 | 0.771 | − 0.7 | − 0.086 | − 0.17414 | − 0.03075 | 0.8986* | − 0.4857 | 0.6 | 0.1 |
ER-Alpha | 0.016 | − 0.714 | 0.0294 | 0.257 | 0.25 | 0.16584 | 0.0425 | 0.4857 | − 0.4857 | 0.3 | 0.1426 | 0.173056 | 0.01357 | 0.3142 | 0.7714 | − 0.657 | − 0.1 |
ER-Beta | − 0.189* | − 0.2 | − 0.264 | − 0.257 | 0.142 | − 0.00069 | − 0.037 | 0.485 | − 0.1428 | 0.4 | − 0.314 | − 0.2009 | − 0.10588 | 0.4286 | − 0.6 | − 0.486 | − 0.6 |
MMEDWB MCF7 cells exposed to WB, MMEDPRP MCF7 cells exposed to PRP, MTAMWB Tamoxifen-treated MCF7 cells exposed to WB, MTAMPRP Tamoxifen-treated MCF7 cells exposed to PRP, WBTAMM MCF7 cells exposed to Tamoxifen-treated WB, PRPTAMM MCF7 cells exposed to Tamoxifen-treated PRP, TMEDWB T47D cells exposed to WB, TMEDPRP T47D cells exposed to PRP, TTAMWB Tamoxifen-treated T47D cells exposed to WB, TTAMPRP Tamoxifen-treated T47D cells exposed to PRP, WBTAMT T47D cells exposed to Tamoxifen-treated WB, PRPTAMT T47D cells exposed to Tamoxifen-treated PRP.
*p < 0.05 compared to thrombin detection, italics p < 0.05 compared to CD62P IPA, bold p < 0.05 compared to CD63 IPA.