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. 2020 Nov 6;10:19256. doi: 10.1038/s41598-020-75779-y

Table 2.

Tabulation showing r values obtained from the nonparametric Spearman’s correlation between CD62P, CD63 IPA and ERα and ERβ, with thrombin detection for MCF7and T47D cells.

Spearman rank order correlations
Highlighted correlations are significant at p < 0.05. r = 0.6
Overall Control Model 1 Model 2
MMEDWB MMEDPRP TMEDWB TMEDPRP MCF7 Overall T47D Overall MTAMWB MTAMPRP TTAMWB TTAMPRP MCF7 Overall T47D Overall WBTAMM PRPTAMM WBTAMT PRPTAMT
Thrombin generation
CD62P IPA − 0.075 − 0.314 0.0857 − 0.028 0.257 − 0.242* 0.1319 − 0.2 0.7714 0.3 0.3142 − 0.24795* − 0.06761 − 0.6572 − 0.486 − 0.579 0.4
CD63 IPA − 0.047 − 0.314 0.0285 0.314 0.428 − 0.195 0.1018 − 0.429 0.771 − 0.7 − 0.086 − 0.17414 − 0.03075 0.8986* − 0.4857 0.6 0.1
ER-Alpha 0.016 − 0.714 0.0294 0.257 0.25 0.16584 0.0425 0.4857 − 0.4857 0.3 0.1426 0.173056 0.01357 0.3142 0.7714 − 0.657 − 0.1
ER-Beta − 0.189* − 0.2 − 0.264 − 0.257 0.142 − 0.00069 − 0.037 0.485 − 0.1428 0.4 − 0.314 − 0.2009 − 0.10588 0.4286 − 0.6 − 0.486 − 0.6

MMEDWB MCF7 cells exposed to WB, MMEDPRP MCF7 cells exposed to PRP, MTAMWB Tamoxifen-treated MCF7 cells exposed to WB, MTAMPRP Tamoxifen-treated MCF7 cells exposed to PRP, WBTAMM MCF7 cells exposed to Tamoxifen-treated WB, PRPTAMM MCF7 cells exposed to Tamoxifen-treated PRP, TMEDWB T47D cells exposed to WB, TMEDPRP T47D cells exposed to PRP, TTAMWB Tamoxifen-treated T47D cells exposed to WB, TTAMPRP Tamoxifen-treated T47D cells exposed to PRP, WBTAMT T47D cells exposed to Tamoxifen-treated WB, PRPTAMT T47D cells exposed to Tamoxifen-treated PRP.

*p < 0.05 compared to thrombin detection, italics p < 0.05 compared to CD62P IPA, bold p < 0.05 compared to CD63 IPA.