. 2020 Nov 6;10:19275. doi: 10.1038/s41598-020-76299-5

Table 4.

Concentrations of nutritional supplements in oxygenator and control groups.

Variable	Group^a	Baseline		1 h		6 h		24 h		p-value
Variable	Group^a	Mean	SD^b	Mean	SD^b	Mean	SD^b	Mean	SD^b	p-value
Cobalamin (pmol/L)	O	175.4	27.9	172.6	30.92	175.5	30.00	184.8	28.78	0.99
Cobalamin (pmol/L)	C	175.8	27.9	173.3	31.89	177.1	25.80	189.2	27.40	0.99
Folate (nmol/L)	O	31.6	3.6	31.50	5.28	33.1	5.19	36.00	5.51	0.92
Folate (nmol/L)	C	31.6	3.6	31.6	4.80	33.1	4.60	41.00	5.00	0.92
Vitamin A (μmol/L)	O	0.84	0.15	0.85	0.12	0.78	0.19	0.63	0.25	0.93
Vitamin A (μmol/L)	C	0.84	0.15	0.83	0.15	0.82	0.16	0.73	0.05	0.93
Potassium (mmol/L)	O	4.34	0.11	4.46	0.19	4.50	0.18	5.21	0.27	0.89
Potassium (mmol/L)	C	4.33	0.22	4.51	0.39	4.51	1.21	5.60	1.21	0.89
Calcuim (mmol/L)	O	1.96	0.02	1.94	0.02	1.96	0.03	2.09	0.06	0.84
Calcuim (mmol/L)	C	1.96	0.02	1.96	0.02	1.96	0.03	2.01	0.05	0.84
Phosphorus (mmol/L)	O	1.76	0.05	1.70	0.06	1.53	0.33	3.71	0.38	0.63
Phosphorus (mmol/L)	C	1.76	0.05	1.85	0.08	1.98	0.29	3.20	0.21	0.63
Magnesium (mmol/L)	O	0.98	0.02	0.96	0.02	0.97	0.01	1.06	0.06	0.82
Magnesium (mmol/L)	C	0.98	0.02	0.96	0.01	0.97	0.03	1.01	0.05	0.82
Glucose (mmol/L)	O	23.94	1.19	22.71	0.89	21.05	0.65	17.80	0.72	0.95
Glucose (mmol/L)	C	23.94	1.19	22.86	0.83	21.40	0.89	14.62	6.04	0.95
LDH^c (U/L)	O	74.80	10.32	80.66	9.75	84.5	8.31	132.6	23.40	1.0
LDH^c (U/L)	C	74.80	10.32	74.16	8.51	99.8	11.72	250.2	93.9	1.0
Apo a^d (g/L)	O	0.54	0.13	0.55	0.12	0.53	0.12	0.56	0.13	0.17
Apo a^d (g/L)	C	0.54	0.13	0.55	0.12	0.55	0.12	0.55	0.10	0.17
Apo b^e (g/L)	O	0.35	0.05	0.32	0.04	0.30	0.07	0.31	0.07	0.25
Apo b^e (g/L)	C	0.35	0.05	0.32	0.04	0.30	0.07	0.33	0.05	0.25
Lipo a^f (g/L)	O	35.25	40.21	34.00	39.02	34.5	40.61	37.00	42.9	1.0
Lipo a^f (g/L)	C	35.25	40.21	36.75	40.35	35.00	40.32	44.00	48.07	1.0
Albumin (g/L)	O	15.80	3.9	16.00	2.60	16.10	2.60	17.00	2.36	1.0
Albumin (g/L)	C	15.80	3.9	17.30	4.30	15.80	2.20	15.70	0.90	1.0
Total protein (g/L)	O	26.80	2.6	26.30	1.90	27.0	2.0	28.50	2.50	0.95
Total protein (g/L)	C	26.80	2.6	26.80	1.90	26.80	1.72	27.75	0.9	0.95
Triglycerides (mmol/L)	O	3.00	0.25	3.03	0.23	3.05	0.21	3.06	0.21	0.86
Triglycerides (mmol/L)	C	3.00	0.25	2.80	0.20	2.85	0.20	2.35	0.60	0.86
LDL^g (mmol/l)	O	1.06	0.6	0.98	0.2	0.98	0.2	1.05	0.2	0.98
LDL^g (mmol/l)	C	1.04	0.2	0.98	0.2	0.98	0.2	0.97	0.29	0.98
HDL^h (mmol/L)	O	0.68	0.22	0.66	0.22	0.66	0.22	0.76	0.25	0.99
HDL^h (mmol/L)	C	0.68	0.22	0.66	0.22	0.66	0.22	0.75	0.20	0.99
Total cholesterol (mmol/L)	O	1.80	0.3	1.78	0.27	1.83	0.25	2.0	0.3	0.94
Total cholesterol (mmol/L)	C	1.80	0.3	1.78	0.27	1.83	0.25	2.0	0.21	0.94

Values are mean and standard deviation. Statistical analyses were performed using mixed models with robust standard errors.

^aGroup O Oxygenator group. C Control group.

^bSD Standard deviation.

^cLDH Lactate dehydrogenase.

^dApo a Apolipoprotein A1.

^eApo b Apolipoprotein B.

^fLipo a Lipoprotein A.

^gLDL Low-density Lipoprotein.

^hHDL High-density Lipoprotein.