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. 2020 Oct 31;2020:5454210. doi: 10.1155/2020/5454210

Figure 4.

Figure 4

Suppression of apoptosis and ROS generation by dexmedetomidine in cells treated with LPS was reversed by overexpression of p75. (a) Western blots and (b) their semiquantitative analyses of p75NTR in the LPS-treated group or the LPS+DEX-treated group; (c) western blots and (d) their semiquantitative analyses of p75NTR in pc/C-transfected group or pc/p75-transfected group; (e) the apoptotic rate of HK-2 cells was determined by flow cytometry; (g) statistical analysis of the apoptotic rate of HK-2 cells; (f) ROS levels of HK-2 cells was determined by flow cytometry; (h) statistical analysis of the ROS fluorescence (∗p < 0.05 and ∗∗p < 0.001 versus control; #p < 0.05 and #p < 0.01 versus LPS. Data were presented as mean ± SEM, n = 6).