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. 2020 Oct 31;2020:8796103. doi: 10.1155/2020/8796103

Figure 1.

Figure 1

Ki20227 administration reduces microglia number. (a) Immunofluorescence staining images of Iba1 in the cortex of WT group and Ki20227-treated mice on days 7 and 14. Scale bar = 100 μm and 50 μm. Merged figure shows positive cells (white arrow). (b) Quantitative analyses of microglia density. WT group vs. Ki20227 administration on day 7, ∗∗∗P < 0.001; WT vs. Ki20227 administration on day 14, ∗∗∗P < 0.001; two-way ANOVA with Bonferroni's posttest, n = 4. Data were presented as mean ± SEM. (c) Quantitative analyses of weight changes after Ki20227 administration. Data were presented as mean ± SEM. One-way ANOVA with Tukey's tests, n = 7. No significant difference between WT and Ki20227 on day 7. WT vs. Ki20227 on day 14, ∗∗∗P < 0.001.